Adipose afferent reflex response to insulin is mediated by melanocortin 4 type receptors in the paraventricular nucleus in insulin resistance rats
Adipose afferent reflex response to insulin is mediated by melanocortin 4 type receptors in the paraventricular nucleus in insulin resistance rats
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DOI：
10.1111/apha.12502
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发表时间：
2015-08
影响因子：
6.3
通讯作者：
L. Ding;N. Tong;X.‐M. Feng;Dan Chen;Hong Wang;Yueyuan Wang;Yuehua Li;Guo-Qing Zhu;Ye-Bo Zhou
中科院分区：
文献类型：
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作者：
L. Ding;N. Tong;X.‐M. Feng;Dan Chen;Hong Wang;Yueyuan Wang;Yuehua Li;Guo-Qing Zhu;Ye-Bo Zhou
脂肪传入反射（AAR）参与交感神经激活和高血压。室旁核（PVN）在AAR和交感神经流出中起重要作用。本研究的目的是确定是否PVN介导的AAR反应胰岛素在大鼠模型的胰岛素抵抗（IR）。
Adipose afferent reflex (AAR) contributes to sympathetic activation and hypertension. Paraventricular nucleus (PVN) plays an important role in AAR and sympathetic outflow. The aim of the present study was to determine whether PVN mediates AAR response to insulin in a rat model of insulin resistance (IR).