COVID-19-related multisystem inflammatory syndrome in adult: the first death in Brazil.
COVID-19-related multisystem inflammatory syndrome in adult: the first death in Brazil.
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DOI：
10.1590/s1678-9946202365050
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发表时间：
2023
影响因子：
1.9
通讯作者：
Estofolete, Cassia Fernanda
中科院分区：
文献类型：
--
作者：
Salomao, Maria Lucia Machado;Queiroz, Flavia;Mendes, Lina de Moura;de Lima, Taiza Maschio;Tuckumantel, Murillo de Souza;Catelan, Marcia Wakai;de Oliveira, Neymar Elias;Nogueira, Mauricio Lacerda;Estofolete, Cassia Fernanda
尽管罕见，但与 COVID-19 相关的多系统炎症综合征的确切发病机制在很大程度上仍然难以捉摸。该综合征的症状常常与其他感染的症状重叠，给及时诊断带来了挑战。一名 34 岁男性患者因怀疑患有严重登革热而入院，并迅速进展为多器官功能障碍。登革热测试结果呈阴性，四天后他去世了。该病例发生在 COVID-19 首次发病后约 4 周，符合疾病控制和预防中心定义的所有诊断标准。本报告介绍了巴西首例有记录的成人致命多系统炎症综合征 (MIS-A) 病例。认识到怀疑这种综合征的重要性并在早期立即开始治疗对于最大限度地减少损害和死亡率至关重要。
The precise pathogenesis of COVID-19-related multisystem inflammatory syndrome remains largely elusive, despite its rarity. The syndrome symptoms often overlap with those of other infections, posing challenges for prompt diagnosis. A male patient, 34 years old, was admitted with suspicion of severe dengue, rapidly progressing to multiple organ dysfunction. Dengue tests resulted negative, and he passed away after four days. This case occurred approximately four weeks after the initial onset of COVID-19 and met all diagnostic criteria as defined by the Centers for Disease Control and Prevention. This report presents the first documented case of fatal multisystem inflammatory syndrome in adult (MIS-A) in Brazil. Recognizing the significance of suspecting this syndrome and promptly initiating treatment at an early stage are essential for minimizing damage and mortality.