Expeditious Synthesis of a Novel C3-Symmetric Receptor that Binds Peptides Sequence-Selectively†
Expeditious Synthesis of a Novel C3-Symmetric Receptor that Binds Peptides Sequence-Selectively†
复制标题
快速合成可选择性结合肽序列的新型 C3 对称受体†
DOI：
10.1002/anie.199424581
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发表时间：
1995
影响因子：
--
通讯作者：
W. Still
中科院分区：
文献类型：
--
作者：
S. Yoon;W. Still
Over 50 000 tripeptides in one go were tested for their binding properties towards receptor 1 (R= CO (CH 2) 2 CO 2 Dye). The tripeptide library was synthesized on polystyrene beads (one compound per bead). These were then mixed with the colored receptor. The few beads that changed color were selected for characterization. Considering its remarkably high sequence selectivity and straightforward synthesis, 1 might well prove to be most useful in the areas of separation and analysis.
