Bacteria in the prostate tissue of men with idiopathic prostatic inflammation
Bacteria in the prostate tissue of men with idiopathic prostatic inflammation
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DOI：
10.1016/s0022-5347(01)65066-3
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发表时间：
1997-03-01
影响因子：
6.6
通讯作者：
Hillier, SL
中科院分区：
文献类型：
--
作者：
Berger, RE;Krieger, JN;Hillier, SL
目的：虽然抗生素是前列腺炎综合征的一线治疗方法，但医生能够记录感染的病例非常少。我们在 85 名无菌尿的受试者中检查了泌尿生殖系统感染与炎症性前列腺炎的关系。材料和方法：评估包括尿道、尿液和经会阴前列腺活检培养物（特别是共生菌和挑剔微生物）以及表达前列腺分泌物的白细胞计数。结果：表达前列腺分泌物发炎的男性 (25) 更有可能进行任何细菌分离（p =与没有表现出前列腺分泌炎症的男性相比，前列腺活检培养物中厌氧菌培养呈阳性（p = 0.03）、细菌总数更高（p = 0.02）和分离出更多细菌种类（p = 0.02）（60）。结论：在某些情况下，前列腺的细菌定植/入侵可能与炎症性前列腺炎有关。
Purpose: Although antibiotics represent the first line of treatment for prostatitis syndromes, physicians can document infection in remarkably few cases. We examined the relationship of genitourinary infection to inflammatory prostatitis in 85 subjects without bacteriuria.Materials and Methods: Evaluation consisted of cultures of urethra, urine and transperineal prostate biopsies, specifically for commensal and fastidious organisms, and leukocyte counts of expressed prostatic secretions.Results: Men with inflamed expressed prostatic secretions (25) were more likely to have any bacterial isolation (p = 0.01), positive cultures for anaerobic bacteria (p = 0.03), higher total bacterial counts (p = 0.02) and more bacterial species isolated (p = 0.02) in prostate biopsy cultures than men without expressed prostatic secretion inflammation (60).Conclusions: Bacterial colonization/invasion of the prostate may be associated with inflammatory prostatitis in some cases.