Neonatal weight loss in breast and formula fed infants
Neonatal weight loss in breast and formula fed infants
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DOI：
10.1136/fn.88.6.f472
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发表时间：
2003-11-01
影响因子：
4.4
通讯作者：
Young, D
中科院分区：
文献类型：
--
作者：
Macdonald, PD;Ross, SRM;Young, D
目的：定义范围内的新生儿体重减轻的人口相对于喂养methods.Design：前瞻性观察性队列study.Setting：产科服务提供地理定义，社区为基础的新生儿following.Participants：971连续足月新生儿出生体重大于或等于2500克在第一个2-3周的生命; 34排除（数据不足）。937包括：45%母乳喂养，42%配方奶粉喂养，13%母乳和配方奶粉喂养。结果测量：最大体重减轻和时间，恢复出生体重的年龄。结果：中位数体重减轻：配方奶粉喂养3.5%，母乳喂养6.6%。最大体重减轻的上百分位数差异很大（第95百分位数：母乳喂养= 11.8%，配方奶粉喂养= 8.4%;第97.5百分位数：母乳喂养= 12.8%，配方奶粉喂养= 9.5%）。最大体重减轻的中位时间：母乳喂养和配方奶粉喂养的2.7天。出生体重恢复：母乳喂养的中位数为8.3天，第95百分位数为18.7天，第97.5百分位数为21.0天;配方奶粉喂养的中位数为6.5天，第95百分位数为14.5天，第97.5百分位数为16.7天。恢复出生体重所需的时间与所有groups.Conclusions的初始体重减轻的程度和时间相关：早期新生儿体重减轻的定义，允许识别婴儿谁值得更密切的评估和支持。
Objective: To define the range of neonatal weight loss in a population relative to feeding method.Design: Prospective observational cohort study.Setting: Maternity service providing geographically defined, community based newborn follow up.Participants: 971 consecutive term newborns of birth weight greater than or equal to 2500 g during the first 2-3 weeks of life; 34 excluded (inadequate data). 937 included: 45% breast fed, 42% formula fed, 13% breast and formula fed.Outcome measures: Maximum weight loss and timing, age on regaining birth weight.Results: Median weight loss: formula fed 3.5%, breast fed 6.6%. Upper centiles for maximum weight loss differ considerably (95th centiles: breast fed = 11.8%, formula fed = 8.4%; 97.5th centiles: breast fed = 12.8%, formula fed = 9.5%). Median time of maximum weight loss: 2.7 days for breast fed and formula fed. Recovery of birth weight: breast fed median 8.3 days, 95th centile 18.7 days, 97.5th centile 21.0 days; formula fed median 6.5 days, 95th centile 14.5 days, 97.5th centile 16.7 days. The time taken to regain birth weight correlates with both the degree and timing of initial weight loss for all groups.Conclusions: Early neonatal weight loss is defined allowing identification of infants who merit closer assessment and support.