Comparative Responsiveness of Pain Measures in Cancer Patients
Comparative Responsiveness of Pain Measures in Cancer Patients
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DOI：
10.1016/j.jpain.2012.05.004
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发表时间：
2012-08-01
期刊：
影响因子：
4
通讯作者：
Krebs, Erin E.
中科院分区：
文献类型：
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作者：
Kroenke, Kurt;Theobald, Dale;Krebs, Erin E.
评估和监测癌症患者疼痛的简单方法是可用的，但很少有不同方法的头对头心理测量比较的报道。对参加印第安纳州癌症疼痛和抑郁(INCPAD)试验的274名患者的基线和3个月数据进行了分析。参与者完成了简明疼痛问卷(BPI)、聚乙二醇量表(BPI的3个项目的缩写版本)、简表(SF)-36疼痛量表和疼痛全球变化评级测量。全球评级被用作标准化反应平均值和接收者操作特征曲线分析的标准。为了评估对试验干预的反应性，我们评估了按试验ARM分层的标准化效应大小统计。所有措施都对全球改善做出反应，区分改善和不改善的参与者，并检测到显著的干预治疗效果。短期和长期措施也同样反应灵敏。此外，将疼痛严重程度和干扰合并为单一评分(BPI总得分、聚乙二醇、SF-36疼痛)的复合测量与每个领域的单独测量(BPI严重程度和BPI干扰)的表现相当。观点：疼痛测量只需2到3项简单的单项评分，对癌症相关疼痛的患者就有反应。超短措施为临床治疗和癌症相关疼痛的研究提供了一种有效和高效的疼痛评估和监测手段。由Elsevier Inc.代表美国疼痛协会出版
Brief measures to assess and monitor pain in cancer patients are available, but few head-to-head psychometric comparisons of different measures have been reported. Baseline and 3-month data were analyzed from 274 patients enrolled in the Indiana Cancer Pain and Depression (INCPAD) trial. Participants completed the Brief Pain Inventory (BPI), the PEG (a 3-item abbreviated version of the BPI), the short form (SF)-36 pain scale, and a pain global rating of change measure. The global rating was used as the criterion for standardized response mean and receiver operating characteristic curve analyses. To assess responsiveness to the trial intervention, we evaluated standardized effect size statistics stratified by trial arm. All measures were responsive to global improvement, discriminated between participants with and without improvement, and detected a significant intervention treatment effect. Short and longer measures were similarly responsive. Also, composite measures that combined pain severity and interference into a single score (BPI total, PEG, SF-36 pain) performed comparably to separate measures of each domain (BPI severity and BPI interference). Perspective: Pain measures as brief as 2 or 3 items that provide a single score are responsive in patients with cancer-related pain. Ultra-brief measures offer a valid and efficient means of assessing and monitoring pain for the clinical management as well as research of cancer-related pain. Published by Elsevier Inc. on behalf of the American Pain Society