Infectious disease hospitalizations among infants in the United States
Infectious disease hospitalizations among infants in the United States
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DOI：
10.1542/peds.2007-1392
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发表时间：
2008-02-01
期刊：
影响因子：
8
通讯作者：
Schonberger, Lawrence B.
中科院分区：
文献类型：
--
作者：
Yorita, Krista L.;Holman, Robert C.;Schonberger, Lawrence B.
OBJECTIVE.本研究描述了美国婴儿感染性疾病住院的负担和流行病学特征。通过使用儿童住院患者数据库，对2003年期间美国婴儿（1岁）住院的主要诊断为感染性疾病的情况进行了检查。研究了传染病住院率、住院率和各种医院参数的全国估计值。在2003年期间，估计有286739例感染性疾病住院发生在美国的婴儿中，占所有婴儿住院的42.8%。全国传染病住院率为每10万活产7010.8例，或相当于每14名婴儿有1例传染病住院。住院时间的中位数为3天，婴儿住院总天数为100万天。男孩和非白人婴儿的传染病住院率最高。婴儿感染性疾病住院治疗中最常见的诊断包括下呼吸道感染（59.0%）、肾脏、尿路和膀胱感染（7.6%）、上呼吸道感染（6.5%）和败血症（6.5%）。在美国婴儿中，传染病住院的中位费用为2235美元，每年的总住院费用约为6.9亿美元。在美国，婴儿中的传染病住院占大量的卫生保健支出和住院时间，其中呼吸系统疾病住院占所有住院的一半以上。年龄较小的婴儿、男孩和非白人婴儿感染性疾病住院的风险增加。减少种族差异和呼吸道感染发生率的措施应能大幅度减少婴儿的传染病负担。
OBJECTIVE. This study describes the burden and epidemiologic features of infectious disease hospitalizations among infants in the United States.METHODS. Hospitalizations with an infectious disease listed as a primary diagnosis for infants ( 1 year of age) in the United States during 2003 were examined by using the Kids' Inpatient Database. National estimates of infectious disease hospitalizations, hospitalization rates, and various hospital parameters were examined.RESULTS. During 2003, an estimated 286 739 infectious disease hospitalizations occurred among infants in the United States and accounted for 42.8% of all infant hospitalizations. The national infectious disease hospitalization rate was 7010.8 hospitalizations per 100 000 live births, or similar to 1 infectious disease hospitalization for every 14 infants. The median length of stay was 3 days, and stays totaled 1 million hospital days for infants. Infectious disease hospitalization rates were highest among boys and nonwhite infants. The most commonly listed diagnoses among the infant infectious disease hospitalizations included lower respiratory tract infections (59.0%), kidney, urinary tract, and bladder infections (7.6%), upper respiratory tract infections (6.5%), and septicemia (6.5%). The median cost of an infectious disease hospitalization was $2235, with total annual hospital costs of approximately $690 million, among infants in the United States.CONCLUSIONS. Infectious disease hospitalizations among infants account for substantial health care expenditures and hospital time in the United States, with respiratory disease hospitalizations constituting more than one half of all hospitalizations. Younger infants, boys, and nonwhite infants were at increased risk for infectious disease hospitalization. Measures to reduce racial disparities and the occurrence of respiratory tract infections should substantially decrease the infectious disease burden among infants.