Weight Trajectories of Israeli Pediatric Cancer Survivors.
Weight Trajectories of Israeli Pediatric Cancer Survivors.
复制标题
以色列小儿癌症幸存者的体重轨迹。
DOI：
10.1093/jpepsy/jsw102
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发表时间：
2017
影响因子：
3.6
通讯作者：
Weintraub,Michael
中科院分区：
文献类型：
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作者：
Stern,Marilyn;Bachar,Eytan;RonenAckerman,Eyal;Rancourt,Diana;Bonne,Omer;Weintraub,Michael
目的：美国儿童癌症幸存者（PCS）中超重/肥胖的高发生率的跨国复制是有限的。从诊断和癌症治疗结束到治疗后3年，研究了以色列PCS患者体重轨迹的预测因子。方法从135例以色列PCS（诊断年龄= 11.4）的病历中计算每个时间点的世界卫生组织导出的体重指数（z-BMI）值。采用包括年龄、种族、性别、治疗时间和诊断作为预测因子的三段式分段多水平模型来估计z-BMI轨迹。结果大多数参与者在所有时间点都保持健康体重。从诊断到治疗结束，诊断为淋巴瘤/白血病的PCS与其他癌症诊断的PCS出现了不同的体重轨迹，但治疗后观察到相似的体重变化模式。结论在以色列的PCS中未观察到美国PCS体重轨迹的重复，提示探索PCS中肥胖的环境危险因素的重要性。
ObjectiveCross-national replication of the high rates of overweight/obesity among U.S. pediatric cancer survivors (PCS) is limited. Predictors of weight trajectories of Israeli PCS were examined from diagnosis and end of active cancer treatment to 3 years posttreatment.MethodsWorld Health Organization-derived body mass index (z-BMI) values were calculated at each time point from medical records of 135 Israeli PCS (Mdiagnosis age = 11.4). A three-section piecewise multilevel model including age, ethnicity, gender, treatment length, and diagnosis as predictors was used to estimate z-BMI trajectories.ResultsMost participants remained at a healthy weight at all time points. Differing weight trajectories emerged for PCS diagnosed with lymphoma/leukemia versus other cancer diagnoses from diagnosis to end of treatment, but similar weight change patterns were observed posttreatment.ConclusionReplication of U.S. PCS weight trajectories was not observed in Israeli PCS, suggesting the importance of exploring environmental risk factors contributing to obesity among PCS.