Controlling the double helix

Controlling the double helix
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DOI:
10.1038/nature01411
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发表时间:
2003-01-23
期刊:
影响因子:
64.8
通讯作者:
Groudine, M
Groudine, M
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Felsenfeld, G;Groudine, M

文献摘要

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染色质是DNA和蛋白质的复合物,其中遗传物质被包装在具有细胞核的生物体的细胞内。染色质结构是动态的,并对基因表达和其他基本细胞过程施加深刻的控制。其结构的变化可以遗传给下一代,而不依赖于DNA序列本身。
Chromatin is the complex of DNA and proteins in which the genetic material is packaged inside the cells of organisms with nuclei. Chromatin structure is dynamic and exerts profound control over gene expression and other fundamental cellular processes. Changes in its structure can be inherited by the next generation, independent of the DNA sequence itself.