Prevalence of hypercalciuria in postmenopausal women with osteoporosis
Prevalence of hypercalciuria in postmenopausal women with osteoporosis
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DOI：
10.1590/s0004-27302012000100001
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发表时间：
2012-02-01
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影响因子：
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通讯作者：
Borba, Victória Zegbi Cochenski
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文献类型：
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作者：
Carvalho, Mauricio;Kulak, Carolina Aguiar Moreira;Borba, Victória Zegbi Cochenski
目的：了解绝经后骨质疏松症妇女高钙尿症(HC)的患病率及其与临床资料和骨矿物质代谢的关系。对象和方法：对127名女性进行24小时尿钙测定。采用双能X线骨密度仪(DXA)测量腰椎和股骨骨密度。结果：平均年龄(+/-SD)为(+/-8)岁。根据尿钙排泄量将患者分为正常钙尿组和高钙尿组。在127例患者中，19例(15%)被列为HC。两组之间唯一的区别是开始绝经的年龄(46+/-6岁vs.50+/-3岁，P<；0.0005)。未发现尿钙与年龄、BMI、BMD、钙、磷、甲状旁腺素和碱性磷酸酶相关。结论：绝经后骨质疏松症患者中HC的发生率较高，对这些患者的调查应包括尿钙测定。ARQ胸罩内分泌激素代谢。2012年；56(1)：1-5
Objective: To determine the prevalence of hypercalciuria (HC) in postmenopausal women with osteoporosis and its relationship with clinical data and bone mineral metabolism. Subjects and methods: Calciuria was measured in 24-hour urine samples of 127 women. BMD was measured in the lumbar spine and femur by dual-energy X-ray absorptiometry (DXA). Results: Mean age (+/- SD) was 64 (+/- 8) years. According to urinary calcium excretion, patients were divided into normo- and hypercalciuric (HC). Of the 127 patients, 19 (15%) were classified as HC. The only difference between the groups was the age of onset of menopause (46 +/- 6 vs. 50 +/- 3 years HC, p < 0.0005). No association was found between calciuria and age, BMI, BMD, calcium, phosphorus, PTH, and alkaline phosphatase. Conclusion: HC is frequent in postmenopausal women with osteoporosis, and calciuria measurement should be included in the investigation of these patients. Arq Bras Endocrinol Metab. 2012;56(1):1-5