Effect of reperfusion on biventricular function and survival after right ventricular infarction

Effect of reperfusion on biventricular function and survival after right ventricular infarction
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DOI:
10.1056/nejm199804023381401
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发表时间:
1998-04-02
影响因子:
158.5
通讯作者:
Goldstein, JA
Goldstein, JA
中科院分区:
医学1区
文献类型:
--
作者:
Bowers, TR;O'Neill, WW;Goldstein, JA

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背景尽管再灌注对左心室梗死患者的有益作用已被充分证明,但对急性右心室梗死患者的益处尚不清楚。方法为了确定直接血管成形术是否改善右心室梗死患者的右心室功能和临床结局,我们对53例急性右心室梗塞患者在血管成形术前后进行了超声心动图检查。结果完全再灌注,定义为右冠状动脉主干及其主要右室分支血流正常,41例患者获得(77%),导致右心室功能迅速和显著恢复(游离壁运动的平均[+/-SE]评分,基线时为3.0+/-0.4,3天时为1.4+/-0.1; P
Background Although the salutary effects of reperfusion in patients with left ventricular infarction are well documented, the benefits in patients with acute right ventricular infarction are less clear.Methods To determine whether primary angioplasty improves right ventricular function and the clinical outcome in patients with right ventricular infarction, we performed echocardiographic studies before and after angioplasty in 53 patients with acute right ventricular infarction.Results Complete reperfusion, defined as normal flow in the right main coronary artery and its major right ventricular branches, was achieved in 41 patients (77 percent), leading to prompt and striking recovery of right ventricular function (mean [+/-SE] score for free-wall motion, 3.0+/-0.4 at base line and 1.4+/-0.1 at three days; P