Stretch sensitization of human muscle spindles.
Stretch sensitization of human muscle spindles.
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DOI：
10.1113/jphysiol.1988.sp017113
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发表时间：
1988-06
期刊：
影响因子：
--
通讯作者：
B. Edin;Å. Vallbo
中科院分区：
文献类型：
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作者：
B. Edin;Å. Vallbo
1.通过显微神经造影术连续记录了67个来自手指伸肌的传入。2.根据这些单位对斜坡和保持拉伸、叠加在斜坡和保持拉伸上的正弦、最大抽搐收缩以及等长收缩和舒张的反应，将其分为初级或次级肌梭传入或高尔基腱器官传入。3.肌肉被反复拉伸，然后保持短或长几秒钟，然后是缓慢的斜坡拉伸。比较两种情况下肌肉传入神经对慢牵拉的反应。4.与肌肉保持长时的反应相比，当肌肉保持短时，38个被归类为初级纺锤体传入的单元中的30个和11个被归类为次级传入的单元中的4个显示出对慢斜坡的增强反应。5.在这方面，18个高尔基体腱器官传入没有表现出任何差异。6.它的结论是，拉伸敏化确实发生在人体肌梭，当存在时，构成了有力的证据，传入起源于肌梭，而不是高尔基体腱器官。此外，由于初级传入和次级传入的反应特征的差异，该测试可能有助于分离肌梭初级传入和次级传入。
1. Sixty‐seven afferents from the finger extensor muscles were consecutively recorded by microneurography. 2. The units were classified as primary or secondary muscle spindle afferents or Golgi tendon organ afferents on the basis of their responses to ramp‐and‐hold stretches, sinusoidals superimposed on ramp‐and‐hold stretches, maximal twitch contractions and isometric contractions and relaxations. 3. The muscle was repeatedly stretched and then either kept short or long for a few seconds followed by a slow ramp stretch. The responses of the muscle afferents to the slow stretch were compared under the two conditions. 4. Thirty out of thirty‐eight units classified as primary spindle afferents and four out of eleven units classified as secondary afferents showed an enhanced response to the slow ramp when the muscle had been kept short compared to the response when the muscle had been kept long. 5. None of the eighteen Golgi tendon organ afferents showed any difference in this respect. 6. It is concluded that stretch sensitization does occur in human muscle spindles and, when present, constitutes firm evidence of the afferent originating from a muscle spindle rather than a Golgi tendon organ. In addition, due to differences in the response characteristics of primaries and secondaries, the test may aid in separating muscle spindle primary afferents from secondary afferents.