ROLE OF ABDUCENS NEURONS IN VESTIBULOOCULAR REFLEX
ROLE OF ABDUCENS NEURONS IN VESTIBULOOCULAR REFLEX
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DOI：
10.1152/jn.1973.36.4.724
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发表时间：
1973-01-01
影响因子：
2.5
通讯作者：
ROBINSON, DA
中科院分区：
文献类型：
--
作者：
SKAVENSKI, AA;ROBINSON, DA
当动物在其环境中移动时，头部的旋转会导致眼睛的代偿运动，从而防止图像过快地扫过视网膜。这种反应被称为前庭眼反射。它的属性和神经基础已被广泛研究（例如，6，8，12，16，17，19，20，32，34）。基于这些研究，图1中的简化图说明了这种反射的作用。上面的路径简单地说明了眼睛在空间中的位置是头部在空间中的位置和眼睛在头部中的位置之间的机械差异。如果大脑没有产生补偿性眼球运动，这条路径将允许头部运动干扰视力（图1，下图）。为了确保眼睛在头部的位置正好与头部在空间中的位置相等和相反，大脑必须能够感知头部的位置。不幸的是，半规管受到头部角加速度的刺激，头部位置的二阶导数。为了恢复位置信息以适当地移动眼睛，前庭眼系统必须执行头部加速度的双重积分;第一积分产生头部速度信号，第二积分产生头部位置信号。
HEAD ROTATIONS produced as an animal moves in its environment lead to compensatory eye movements which prevent images from sweeping across the retina too quickly. This response is known as the vestibuloocular reflex. Its properties and neural bases have been investigated extensively (eg, 6, 8, 12, 16, 17, 19, 20, 32, 34). Based on these studies, the simplified diagram in Fig. 1 illustrates the action of this reflex. The upper path simply illustrates that eye position in space is the mechanical difference between head position in space and eye position in the head. This path would allow head motion to disturb vision if compensatory eye movements were not generated by the brain (lower path, Fig. 1). To insure that eye position in the head is just equal and opposite to head position in space, the brain must be able to sense head position. Unfortunately, the semicircular canals are stimulated by angular acceleration of the head, the second derivative of head position. In order to recover position information to move the eye appropriately, the vestibuloocular system must perform a double integration of head acceleration; the first integration yielding a head-velocity signal and the second, a head-position signal.