SUBCORTICAL PROJECTIONS TO THE PONTINE NUCLEI IN THE CAT
SUBCORTICAL PROJECTIONS TO THE PONTINE NUCLEI IN THE CAT
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DOI：
10.1002/cne.902820303
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发表时间：
1989-04-15
影响因子：
2.5
通讯作者：
AAS, JE
中科院分区：
文献类型：
--
作者：
AAS, JE
为了追踪猫从脑干和间脑到脑桥核的所有投射，在 21 只猫的脑桥核中植入并注射了辣根过氧化物酶-小麦胚芽凝集素 (HRP-WGA) 或 Fluro-Gold。在大多数情况下，没有证据表明示踪剂的扩散排除了桥核。脑干和间脑中逆行标记的细胞被仔细绘制和计数。脑干和间脑中标记细胞的数量范围从 24 个（植入量非常小）到 3,490 个（脑桥核注射量大）（从每五个切片计数）。标记的细胞位于双侧，以同侧为主。大量注射后，25-38%的标记细胞位于脑干网状结构，10-16%位于顶盖前核团，10-15%位于下丘脑，7-9%位于未定带，3-9%位于福雷尔视野，4-5%位于蓝斑核，3-5%位于腹外侧膝状体， 2-4% 位于上丘，3% 位于导水管周围灰质，14-15% 位于脑干其他部分。从小示踪剂沉积物完全局限于脑桥核的病例来看，皮层下输入似乎有两种类型：来自网状结构、蓝斑核、导水管周围灰质和中缝核的投射是广泛的，可能到达脑桥核的所有部分，而来自多种其他来源的投射是局部的，仅或主要到达脑桥核的有限部分。
In a systematic attempt to trace all projections from the brainstem and diencephalon to the pontine nuclei of the cat, implantations and injections of horseradish peroxidase-wheat germ agglutinin (HRP-WGA) or Fluro-Gold were placed in the pontine nuclei of 21 cats. In most of the cases there was not evidenced of spread of tracer oustide the pontaine nuclei. Retrogradely labeled cells in the brainstem and diencephalon were carefully mapped and counted. The number of labelled cells in the brainstem and diencephalon ranged from 24 in cases with very small inplantations to 3,490 in cases with large injections in the pontine nuclei (counts from every fifth section). The labeled cells are located bilaterally with an ipsilateral preponderance. After large injections, 25-38% of the labelled cells were located in the brainstem reticular formation, 10-16% in the pretecal nuclei, 10-15% in the hypothalamus, 7-9% in the zona incerta, 3-9% in the fields of Forel, 4-5% in the nucleus locus coeruleus, 3-5% in the ventral lateral geniculate body, 2-4% in the superior colliculus, 3% in the periaqueductal gray, and 14-15% in other parts of the brainstem. Judging from cases with small tracer deposits entirely confined to the pontine nuclei, there appear to be two types of subcortical inputs: Projections from the reticular formation, the nucleus locus coeruleus, the periaqueductal gray, and the raphe nuclei are widespread, presumably reaching all parts of the pontine nuclei, while projections from a diversity of other sources are localized, reaching limited parts of the pontine nuclei only or predominantly.