The enantioface-differentiating (asymmetric) hydrogenation of the C=O double bond with modified raney nickel. XXXVI. The development of modified nickel catalysts with high enantioface-differentiating abilities.
The enantioface-differentiating (asymmetric) hydrogenation of the C=O double bond with modified raney nickel. XXXVI. The development of modified nickel catalysts with high enantioface-differentiating abilities.
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用改性雷尼镍对 C=O 双键进行对映异构（不对称）氢化。
DOI：
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发表时间：
1981
期刊：
影响因子：
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通讯作者：
Y. Izumi
中科院分区：
文献类型：
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作者：
T. Harada;Mihoko Yamamoto;S. Onaka;M. Imaida;H. Ozaki;A. Tai;Y. Izumi
制备了各种类型的改性镍催化剂，并考察了它们的对映体区分（不对称）能力。发现催化剂中铝或相关金属化合物的存在不利于有效的对映体区分催化剂。用酒石酸和无机盐溶液对骨架镍和还原镍催化剂进行改性，得到了高的对映体区分能力。在所考察的改性镍催化剂中，用酒石酸和溴化钠改性的雷尼镍在加氢活性和对映体区分能力方面给出了最好的结果（光学产率88%）。NaBr吸附在Raney镍上，发现抑制非对映体区分氢化。
Various types of modified nickel catalysts were prepared and their enantioface-differentiating (asymmetric) abilities were examined. It was found that the presence of aluminum or related metal compounds in the catalyst was unfavorable for the effective enantioface-differentiating catalyst. The modification with a solution containing tartaric acid and inorganic salt gave a high enantioface-differentiating ability to Raney nickel and reduced nickel catalyst. Among the modified nickel catalysts examined, the Raney nickel modified with tartaric acid and sodium bromide gave the best result with respect to the hydrogenation activity and enantioface-differentiating ability (optical yield 88%). NaBr adsorbed on Raney nickel was found to inhibit the nonenantioface-differentiating hydrogenation.