Cardiovascular reactivity to acute stress associated with sickness absence among Japanese men and women: A prospective study
Cardiovascular reactivity to acute stress associated with sickness absence among Japanese men and women: A prospective study
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DOI：
10.1002/brb3.1541
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发表时间：
2020-02-20
影响因子：
3.1
通讯作者：
Iso, Hiroyasu
中科院分区：
文献类型：
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作者：
Hirokawa, Kumi;Ohira, Tetsuya;Iso, Hiroyasu
目的在前瞻性研究中探讨日本男性和女性对急性应激的心血管反应与疾病缺勤的关系。方法对2006-2009年间接受心理健康检查的111名健康在职日本员工的数据进行分析。计算血压、脉率、外周血流量(PBF)和心率变异性(HRV)(高频[HF]和低频[LF])的变化，计算两种任务之间的差异，包括镜面绘制应力[MDS]和迷宫任务，以及后时间值。通过邮寄调查(平均随访2.3年)对病假进行跟踪调查，直至2010年3月。结果12例因病请假的受试者中，有8例因精神疾病缺勤。在MDS和迷宫任务中低频的变化以及在MDS任务中的LF/HF比率与所有疾病缺席呈正相关(优势比[OR]，95%可信区间[CI]分别为2.09，1.03-4.22；2.04，1.09-3.82；3.10，1.46-6.58)。在MDS任务中，PBF的变化也与疾病消失的风险增加相关(OR，95%CI：2.53，1.10~5.81)。
Objective We aimed to investigate associations between cardiovascular reactivity to acute stress and sickness absence among Japanese male and female workers, in a prospective study.Methods Among healthy employed Japanese workers who underwent mental health checks between 2006 and 2009, data of 111 participants were analyzed. Changes in blood pressure, pulse rate, peripheral blood flow (PBF), and heart rate variability (HRV) (high frequency [HF] and low frequency [LF]) were calculated using differences between the two tasks, mirror drawing stress [MDS] and a maze task, and the postperiod value. Sickness absence through March 2010 was followed up by mail survey (average follow-up 2.3 years). Logistic regression analysis was used, adjusting for lifestyle factors.Results Among 12 participants who took sickness absences, eight were owing to mental problems. Changes in the LF during the MDS and maze tasks and LF-to-HF ratio during the MDS task were positively associated with all sickness absences (odds ratio [OR], 95% confidence interval [CI]: 2.09, 1.03-4.22; 2.04, 1.09-3.82; and 3.10, 1.46-6.58, respectively). Changes in PBF during the MDS task were also associated with increased risk of sickness absence (OR, 95% CI: 2.53, 1.10-5.81).Conclusion Cardiovascular reactivity to acute stress should be considered at workers' health checks.