On the Trapping of Vinylgold Intermediates
On the Trapping of Vinylgold Intermediates
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DOI：
10.1002/adsc.201000011
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发表时间：
2010-04-01
影响因子：
5.4
通讯作者：
Rominger, Frank
中科院分区：
文献类型：
--
作者：
Hashmi, A. Stephen K.;Ramamurthi, Tanuja Dondeti;Rominger, Frank
以N，N‘-bis(2，6-diisopropylphenyl)imidazol-2-ylidene-gold对甲苯磺酸盐[(IPR)AuOTS]和三乙胺为化学计量比的芳基取代邻炔基苯酚和类似的苯胺，得到饱和杂环作为相应的金(I)催化的氢氧基化和氢胺化反应的稳定中间体。对两种产物进行了X-射线晶体结构分析。类似的内部烷基取代邻炔基酚只得到环异构化产物，没有检测到饱和中间体。
An internal aryl-substituted ortho-alkynylphenol and a similar aniline with stoichiometric amounts of N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene-gold tosylate [(IPr)AuOTs] and triethylamine gave the aurated heterocycles as stable intermediates of the corresponding gold(I)-catalysed hydrooxylation and hydroamination reactions. X-ray crystal structure analyses of both products could be obtained. A similar internal alkyl-substituted ortho-alkynylphenol gave only the cycloisomerised product, no aurated intermediate could be detected.