Physical activity and fatigue in breast cancer and multiple sclerosis: psychosocial mechanisms.
Physical activity and fatigue in breast cancer and multiple sclerosis: psychosocial mechanisms.
复制标题
DOI：
10.1097/psy.0b013e3181c68157
复制
发表时间：
2010-01
影响因子：
3.3
通讯作者：
Courneya KS
中科院分区：
文献类型：
--
作者：
McAuley E;White SM;Rogers LQ;Motl RW;Courneya KS
为了在两个研究样本中检查自我效能和抑郁作为从体力活动到疲劳的潜在途径的作用：乳腺癌幸存者（BCS；N=192）和多发性硬化症患者（MS；N=292）。我们假设体力活动通过影响自我效能和抑郁症状而与疲劳间接相关。在协方差建模框架内进行横截面路径分析（BCS）和纵向面板模型（MS）。身体活动对自我效能有直接影响，反过来，自我效能既对疲劳有直接影响，又通过两个样本的抑郁症状产生间接影响。在 MS 样本中，体力活动也对疲劳有直接影响。所有模型拟合指数都非常好。在控制人口统计和健康状况指标时，这些关联仍然很重要。我们的研究结果表明，至少支持一组从体力活动到疲劳的心理社会途径，这是慢性病的一个重要问题。后续工作可能会在其他患病人群中复制这种关联，并尝试确定模型关系是否会随着身体活动干预而改变，以及其他已知的疲劳相关因素（例如睡眠受损和炎症）在多大程度上可以纳入该模型。
To examine the role of self-efficacy and depression as potential pathways from physical activity to fatigue in two study samples: breast cancer survivors (BCS; N=192) and individuals with multiple sclerosis (MS; N=292). We hypothesized that physical activity would be indirectly associated with fatigue through its influence on self-efficacy and depressive symptomatology. A cross-sectional path analysis (BCS) and a longitudinal panel model (MS) were conducted within a covariance modeling framework. Physical activity had a direct effect on self-efficacy, and in turn, self-efficacy had both a direct effect on fatigue and an indirect effect through depressive symptomatology in both samples. In the MS sample, physical activity also had a direct effect on fatigue. All model fit indices were excellent. These associations remained significant when controlling for demographics and health status indicators. Our findings suggest support for at least one set of psychosocial pathways from physical activity to fatigue, an important concern in chronic disease. Subsequent work might replicate such associations in other diseased populations and attempt to determine whether model relations change with physical activity interventions, and the extent to which other known correlates of fatigue such as impaired sleep and inflammation can be incorporated into this model.