A Chinese cross-sectional study on depression and anxiety symptoms in patients with psoriasis vulgaris
A Chinese cross-sectional study on depression and anxiety symptoms in patients with psoriasis vulgaris
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DOI：
10.1080/13548506.2018.1529323
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发表时间：
2019-03-16
影响因子：
3.8
通讯作者：
Shao, Chunhong
中科院分区：
文献类型：
--
作者：
Tian, Zhen;Huang, Yike;Shao, Chunhong
先前的研究报告称，与普通人群相比，银屑病患者的抑郁和焦虑发生率较高，这对评估和治疗具有重要意义。在这项研究中，我们确定了中国银屑病患者抑郁和焦虑的频率及其与疾病严重程度和其他人口统计学变量的关系。该研究包括208例中国寻常型银屑病患者。采用患者健康问卷（PHQ-9）和广泛性焦虑量表（GAD-7）筛查抑郁和焦虑。银屑病面积和严重程度指数（PASI）用于评估银屑病的严重程度。在纳入研究的208名患者中，29名患者（13.9%）为中度至重度抑郁症（PHQ-9 >= 10）阳性，22名患者（10.6%）为焦虑症（GAD-7 >= 10）阳性。认为压力是银屑病加重因素的阳性压力反应者和中度至重度银屑病患者均被发现是中度至重度抑郁或焦虑症状存在的阳性预测因子，而较长的持续时间和晚发年龄起保护作用。在中国银屑病患者样本中，抑郁和焦虑的患病率具有临床意义。我们的研究表明，中国银屑病患者应筛查精神共病。
Previous studies have reported a higher incidence of depression and anxiety in psoriasis patients compared to the general population, which has important implications for assessment and treatment. In this study, we determined the frequency of depression and anxiety in Chinese patients with psoriasis and its relationship with disease severity and other demographic variables. The study included 208 Chinese patients with psoriasis vulgaris. The Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder scale (GAD-7) were used to screen for depression and anxiety. The Psoriasis Area and Severity Index (PASI) was used to assess the severity of psoriasis. Of the 208 patients included in the study, 29 patients (13.9%) were positive for moderate-to-severe depression (PHQ-9 >= 10) and 22 patients (10.6%) were positive for anxiety (GAD-7 >= 10) symptoms. Both positive stress reactors who perceived stress as an exacerbating factor of psoriasis and moderate-to-severe psoriasis were found to be positive predictors for the presence of moderate-to-severe depression or anxiety symptoms while longer duration and late onset age played a protective role. In the sample of Chinese patients with psoriasis there was a clinically significant prevalence of depression and anxiety. Our study suggests that Chinese psoriasis patients should be screened for psychiatric comorbidities.