A NEW VIRUS ISOLATED FROM HUMAN RESPIRATORY TRACT
A NEW VIRUS ISOLATED FROM HUMAN RESPIRATORY TRACT
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DOI：
10.3181/00379727-121-30734
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发表时间：
1966-01-01
影响因子：
--
通讯作者：
PROCKNOW, JJ
中科院分区：
文献类型：
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作者：
HAMRE, D;PROCKNOW, JJ
描述了从人类呼吸道中分离出五种新病毒的情况。其中四人患有轻度非发热上呼吸道感染。该病毒229E是乙醚敏感的RNA，大小约89μm，在人肾和人二倍体细胞中生长，但不在猴肾或H. Ep中生长。 2种文化。它不会使豚鼠红细胞发生血凝。它不能被以下任何抗血清中和：呼吸道合胞体、麻疹、流行性腮腺炎、副流感 1、2、3、4、SV-5、丙型流感。分离出该病毒的 5 个人的配对血清显示中和抗体滴度上升，除一人外，所有人的 CF 抗体也都上升。
The isolation of five strains of a new virus from the human respiratory tract is described. Four of the individuals had mild afebrile upper respiratory infections. The virus, 229E, is ether-sensitive, RNA, about 89 mu in size, and grows in human kidney and human diploid cells but not in monkey kidney or H. Ep. 2 cultures. It does not hemagglutinate guinea pig red cells. It is not neutralized by any of the following anti-sera: respiratory syncytial, measles, mumps, parainfluenza 1, 2, 3, 4, SV-5, influenza C. Paired sera of the five persons from whom this virus was isolated showed rises in neutralizing antibody titer, and all but one also had rises in CF antibody.