New insights regarding the atrial flutter reentrant circuit : studies in the canine sterile pericarditis model.
New insights regarding the atrial flutter reentrant circuit : studies in the canine sterile pericarditis model.
复制标题
关于心房扑动折返回路的新见解：犬无菌性心包炎模型的研究。
DOI：
10.1161/01.cir.100.12.1354
复制
发表时间：
1999
期刊：
影响因子：
37.8
通讯作者：
Waldo,AL
中科院分区：
文献类型：
--
作者：
Uno,K;Kumagai,K;Khrestian,CM;Waldo,AL
背景-在犬无菌心包炎模型中，我们研究了诱发心房扑动时的心房激动，以验证心房扑动折返回路包括间隔成分的假设。方法和结果：我们研究了9只犬诱发的10次持续性(5分钟)的心房扑动。在所有的事件中，折返回路都包括一个间隔成分。6例中有2个折返环，一个位于右房游离壁，另一个累及房间隔、巴赫曼束和右房游离壁，两个环路在右房游离壁共享一条通路(8字形)。第二环间隔波前向(上或下)与右房游离壁环的方向(分别顺时针或逆时针)相关。右房游离壁的一条功能性阻滞线是两个折返环的一部分。在其他4次房扑发作中，仅有1次折返回路出现，其中2次为间隔由下至上，2次为右房游离壁由上至下，2次为相反方向。在所有的心房扑动发作中，心电II导联的扑动波极性由左房的激活方向决定，当方向高于下位时为正极，当方向低于上位时为负极。结论：在这种心房扑动模型中，折返回路(1)总是含有间隔成分，(2)并不总是需要右心房游离壁折返回路，(3)当右心房游离壁存在折返回路时，表现为“8”字形折返，(4)与右房游离壁的一条功能阻滞线有关。
Background—We studied atrial activation during induced atrial flutter in the canine sterile pericarditis model to test the hypothesis that the atrial flutter reentrant circuit includes a septal component.Methods and Results—We studied 10 episodes of induced, sustained (>5 minutes) atrial flutter in 9 dogs. In all episodes, the reentrant circuit included a septal component. In 6 episodes, there were 2 reentrant circuits, one in the right atrial free wall and the second involving the atrial septum, Bachmann’s bundle, and the right atrial free wall; both circuits shared a pathway in the right atrial free wall (figure-of-eight). The direction (superior or inferior) of the septal wave front of the second circuit correlated with the direction (clockwise or counterclockwise, respectively) of the right atrial free-wall circuit. A line of functional block in the right atrial free wall was part of both reentrant circuits. In the other 4 atrial flutter episodes, only 1 reentrant circuit was present, with activation in an inferior-to-superior direction in the septum and a superior-to-inferior direction in the right atrial free wall in 2 episodes and in the opposite direction in the other 2 episodes. In all atrial flutter episodes, the flutter wave polarity in ECG lead II was determined by the direction of activation in the left atrium; polarity was positive when the direction was superior to inferior and negative when the direction was inferior to superior.Conclusions—In this model of atrial flutter, the reentrant circuit (1) always included a septal component, (2) did not always require a right atrial free-wall reentrant circuit, (3) demonstrated figure-of-eight reentry when a reentrant circuit was present in the right atrial free wall, and (4) was associated with a line of functional block in the right atrial free wall.
登录
查看更多内容
犬无菌性心包炎模型中的马戏团运动心房扑动。
影响因子：
24
作者：
W. Schoels;B. Offner;J. Brachmann;W. Kuebler;N. El
通讯作者：
N. El
影响因子：
37.8
作者：
NIWANO, S;ORTIZ, J;WALDO, AL
通讯作者：
WALDO, AL
影响因子：
37.8
作者：
Ortiz,J;Nozaki,A;Shimizu,A;Khrestian,C;Rudy,Y;Waldo,AL
通讯作者：
Waldo,AL
影响因子：
20.1
作者：
W. Hayden;E. Hurley;D. A. Rytand
通讯作者：
D. A. Rytand
DOI：
10.1620/tjem.60.197
发表时间：
1954
期刊：
The Tohoku journal of experimental medicine
影响因子：
--
作者：
Eiichi Kimura;K. Kato;Satoru Murao;Hidero Ajisaka;Shintaro Koyama;Z. Omiya
通讯作者：
Z. Omiya