Nonlinear acoustical response of coated microbubbles in diagnostic ultrasound

Nonlinear acoustical response of coated microbubbles in diagnostic ultrasound
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DOI:
10.1109/ultsym.1994.401889
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发表时间:
1994
期刊:
1994 Proceedings of IEEE Ultrasonics Symposium
影响因子:
--
通讯作者:
Uhlendorf;Christian HofEnann
Uhlendorf;Christian HofEnann
中科院分区:
其他
文献类型:
--
作者:
Uhlendorf;Christian HofEnann

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在新型超声造影剂舒舒563A中使用了包覆一层可生物降解聚合物薄壳的微泡。这些颗粒是耐用的线性散射体,在低声压幅度下可长时间使用。它们会在诊断超声的范围内以较高的幅度立即破裂,从而产生一种称为“声刺激声发射”的瞬时非线性响应。讨论了这种效应的特点以及在新的和非常敏感的常规成像模式和谐波成像模式中的一些潜在应用
Microbubbles coated with a thin biodegradable polymer shell are used in SHU 563 A, a new kind of ultrasound contrast medium. These particles are durable linear scatterers for prolonged times at low acoustic pressure amplitudes. They will immediately rupture at higher amplitudes within the range of diagnostic ultrasound causing a transient nonlinear response termed “Acoustically Stimulated Acoustic Emission”. Characteristics of this effect and some potential applications in novel and extraordinary sensitive conventional and Harmonic Imaging modes are discussed