Assessment of intrafractional movement and internal motion in radiotherapy of rectal cancer using megavoltage computed tomography
Assessment of intrafractional movement and internal motion in radiotherapy of rectal cancer using megavoltage computed tomography
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DOI：
10.1016/j.ijrobp.2008.02.032
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发表时间：
2008-07-01
影响因子：
7
通讯作者：
Storme, Guy
中科院分区：
文献类型：
--
作者：
Tournel, Koen;De Ridder, Mark;Storme, Guy
目的：本研究的目的是提供估计的设置和内部边界的患者治疗直肠癌使用螺旋断层治疗，并评估可能的边缘调整。使用螺旋断层治疗，可以创建高度适形的剂量分布，并且集成的兆伏计算机断层扫描（MVCT）模式允许非常精确的日常患者定位。然而，在临床协议中，仍然应用源自传统设置程序的边缘。这项工作调查是否这种方式可以帮助重新定义治疗margins.Methods和材料：10例接受断层治疗的患者进行MVCT扫描前后10次治疗。使用自动配准，通过骨性标志研究必要的设置边缘。通过描绘和描述直肠系膜movement.Results的内缘进行评估：基于骨性标志，运动的患者在治疗过程中被限制为2.45毫米，1.99毫米，和1.09毫米的横向，纵向和垂直方向，分别。系统误差仅限于
Purpose: The aim of this study was to provide estimates of setup and internal margins of patients treated for rectal carcinoma using helical tomotherapy and to assess possible margin adaptations. Using helical tomotherapy, highly conformal dose distributions can be created, and the integrated megavoltage computed tomography (MVCT) modality allows very precise daily patient positioning. In clinical protocols, however, margins originating from traditional setup procedures are still being applied. This work investigates whether this modality can aid in redefining treatment margins.Methods and Materials: Ten patients who were treated with tomotherapy underwent MVCT scanning before and after 10 treatments. Using automatic registration the necessary setup margin was investigated by means of bony landmarks. Internal margins were assessed by delineating and describing the mesorectal movement.Results: Based on bony landmarks, movement of patients during treatments was limited to 2.45 mm, 1.99 mm, and 1.09 mm in the lateral, longitudinal, and vertical direction, respectively. Systematic errors were limited to