High-Throughput Generation of Emulsions and Microgels in Parallelized Microfluidic Drop-Makers Prepared by Rapid Prototyping
High-Throughput Generation of Emulsions and Microgels in Parallelized Microfluidic Drop-Makers Prepared by Rapid Prototyping
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DOI：
10.1021/acsami.5b03969
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发表时间：
2015-06-17
影响因子：
9.5
通讯作者：
Kuehne, Alexander J. C.
中科院分区：
文献类型：
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作者：
Femmer, Tim;Jans, Alexander;Kuehne, Alexander J. C.
我们描述了快速原型并行微流控液滴制造装置的制备。该制造技术便于液滴制造器垂直地堆叠在彼此的顶部上，从而允许通过分配通道的有效设计来减小占地面积和最小化死体积。我们展示了微流体增材制造技术的潜力和并行设备的性能，通过生产大量的微凝胶直径约为。500 μm，这是使用传统合成方法无法达到的尺寸。
We describe the preparation of rapid prototyped parallelized microfluidic drop-maker devices. The manufacturing technique facilitates stacking of the drop-makers vertically on top of each other allowing for a reduced footprint and minimized dead-volume through efficient design of the distribution channels. We showcase the potential of the additive manufacturing technique for microfluidics and the performance of the parallelized device by producing large amounts of microgels with a diameter of ca. 500 μm, a size that is inaccessible using traditional synthetic approaches.