Plasma needle for in vivo medical treatment:: recent developments and perspectives
Plasma needle for in vivo medical treatment:: recent developments and perspectives
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DOI：
10.1088/0963-0252/15/4/s03
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发表时间：
2006-11-01
影响因子：
3.8
通讯作者：
Steinbuch, M.
中科院分区：
文献类型：
--
作者：
Stoffels, E.;Kieft, I. E.;Steinbuch, M.
在本文中，我们描述了迄今为止关于低温大气等离子体与活细胞和组织相互作用的未解事实。一个特殊设计的源，等离子针，是一个低功率放电，在组织损伤的阈值下工作。如果使用得当，针头不会造成致命的细胞损伤，从而导致细胞死亡（坏死）。相反，它允许通过所谓的细胞脱离精确和局部的细胞移除。此外，血浆可用于细菌消毒。由于治疗条件温和，血浆消毒可在体内进行，例如在伤口和龋齿上进行。目前，人们努力获得对操作装置的更好的控制。因此，使用各种诊断方法对等离子体进行了表征，并设计了一个智能系统，用于相对于处理表面定位设备。
In this paper we describe the hitherto unravelled facts on the interactions of a cold atmospheric plasma with living cells and tissues. A specially designed source, plasma needle, is a low-power discharge, which operates under the threshold of tissue damage. When applied properly, the needle does not cause fatal cell injury which would result in cell death ( necrosis). Instead, it allows precise and localized cell removal by means of the so-called cell detachment. In addition, plasma can be used for bacterial disinfection. Because of mild treatment conditions, plasma disinfection can be performed in vivo, e. g. on wounds and dental cavities. Presently, one strives to obtain a better control of the operating device. Therefore, plasma has been characterized using a variety of diagnostics, and a smart system has been designed for the positioning of the device with respect to the treated surface.