Quantum-Dot-Tagged Reduced Graphene Oxide Nanocomposites for Bright Fluorescence Bioimaging and Photothermal Therapy Monitored In Situ
Quantum-Dot-Tagged Reduced Graphene Oxide Nanocomposites for Bright Fluorescence Bioimaging and Photothermal Therapy Monitored In Situ
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DOI：
10.1002/adma.201104070
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发表时间：
2012-04-03
影响因子：
29.4
通讯作者：
Chen, San-Yuan
中科院分区：
文献类型：
--
作者：
Hu, Shang-Hsiu;Chen, Yu-Wei;Chen, San-Yuan
内化到靶向肿瘤细胞中的量子点标记的还原氧化石墨烯（QD-rGO）纳米复合材料（左）显示来自QD的明亮荧光（右）;通过吸收入射在rGO上的NIR辐射并将其转化为热量，它们还导致同时的细胞死亡和荧光减少（底部）。因此，该纳米复合材料能够用于肿瘤成像、光热治疗和原位监测进行中的治疗。
Quantum-dot-tagged reduced graphene oxide (QD-rGO) nanocomposites (left) internalized into targeted tumor cells display bright fluorescence from the QDs (right); by absorbing NIR radiation incident on the rGO and converting it into heat, they also cause simultaneous cell death and fluorescence reduction (bottom). The nanocomposite is thus capable of tumor imaging, photothermal therapy and in situ monitoring of treatment in progress.