Influence of heat treatment on the mechanical properties, corrosion behavior, and biocompatibility of Zr56Al16Co28 bulk metallic glass
Influence of heat treatment on the mechanical properties, corrosion behavior, and biocompatibility of Zr56Al16Co28 bulk metallic glass
复制标题
DOI：
10.1016/j.jnoncrysol.2014.12.018
复制
发表时间：
2015-03
影响因子：
3.5
通讯作者：
Rongrong Wang;Yingying Wang;Jie Yang;Jiaming Sun;L. Xiong
中科院分区：
文献类型：
--
作者：
Rongrong Wang;Yingying Wang;Jie Yang;Jiaming Sun;L. Xiong
采用动态力学分析（DMA）、电化学分析、体外血液相容性试验和体内生物相容性试验研究了热处理对Zr56Al16Co28块体非晶合金（BMG）力学性能、腐蚀行为和生物相容性的影响。通过对铸态Zr56Al16Co28非晶合金在低于或高于玻璃化转变温度（Tg）下进行热处理，得到了非晶、半晶和完全晶化的Zr56Al16Co28合金。当温度低于Tg时，模量随温度的升高而略有下降，而当温度高于Tg时，由于晶相的出现，模量急剧增加。在低于Tg的温度下热处理后，钝化电位没有变化，但在高于Tg的温度下，钝化电位显著降低，表明Zr56Al16Co28 BMG具有比晶化Zr56Al16Co28合金更好的耐蚀性。Zr56Al16Co28合金具有良好的抗溶血性，且其溶血率低于晶化态合金。体内生物相容性测试表明，铸态Zr56Al16Co28 BMG与结构松弛的BMG具有相似的生物相容性，但比晶化的BMG具有更好的生物相容性。与植入结晶对应物的小鼠相比，植入Zr56Al16Co28BMG的小鼠显示出较低程度的炎症浸润反应。结果表明，铸态Zr 56 Al 16 Co 28 BMG的性能与弛豫态相当，但优于晶态样品的上级性能。
This paper reports the influence of heat treatment on the mechanical properties, corrosion behavior and biocompatibility of Zr56Al16Co28bulk metallic glass (BMG) investigated by dynamic mechanical analysis (DMA), electrochemical analysis in vitro hemocompatibility and in vivo experiments. Zr56Al16Co28alloys with amorphous, semi-crystalline and fully crystallized microstructures were obtained by thermal treatment of as-cast Zr56Al16Co28BMG below or above glass transition temperature (Tg). The modulus slightly decreased with increasing temperature below Tgwhereas the modulus dramatically increased treated above Tgdue to the appearance of crystalline phase. The passivation potential did not change for samples heat-treated below Tgbut decreased significantly above Tg, which indicated that Zr56Al16Co28BMG possessed better corrosion resistance than crystallized Zr56Al16Co28alloys. Zr56Al16Co28alloys showed good hemolytic resistance regardless of the microstructural condition and presented lower hemolytic rate than their crystallized counterparts. In vivo test revealed that as-cast Zr56Al16Co28BMG presented similar biocompatibility to the structurally relaxed BMG and better biocompatibility than the crystallized counterparts. Mice implanted with Zr56Al16Co28BMGs showed lower degree of inflammatory infiltration response compared to mice implanted with the crystallized counterparts. The results showed that the properties of as-cast Zr56Al16Co28BMG were generally comparable to its structurally relaxed counterpart and superior to the crystalline samples.