Opsoclonus–myoclonus as a manifestation of Lyme disease
Opsoclonus–myoclonus as a manifestation of Lyme disease
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眼阵挛-肌阵挛是莱姆病的一种表现
DOI：
10.1136/jnnp.2006.091728
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
F. Mauguière
中科院分区：
文献类型：
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作者：
Laurence M. Peter;Jae Sung Jung;C. Tilikete;P. Ryvlin;F. Mauguière
眼阵挛-肌阵挛综合征（OMS）是一种罕见的疾病，包括与肌阵挛和共济失调相关的混乱的多向扫视眼球运动。在成人中，它通常被认为是一种自身免疫性疾病，发生在副肿瘤背景下或中枢神经系统感染后。我们报告的情况下，病人谁提出的经典功能的OMS表现为急性伯氏疏螺旋体感染的血清和脑脊液检查显示。经过长期抗生素治疗后，结局良好。莱姆病可以被添加到OMS中筛选的病因列表中，因为它可以有效治疗并避免不必要的调查。
Opsoclonus–myoclonus syndrome (OMS) is a rare condition that includes chaotic multidirectional saccadic eye movements associated with myoclonus and ataxia. In adults, it is usually considered to be an autoimmune disease occurring either in a paraneoplastic context or after central nervous system infection. We report the case of a patient who presented with the classic features of OMS as a manifestation of acute Borrelia burgdorferi infection that was shown both on serum and cerebrospinal fluid examination. The outcome was favourable after prolonged antibiotic treatment. Lyme disease could be added to the list of aetiologies to be screened in OMS, as it would allow effective treatment and avoidance of unnecessary investigations.