Dynamics of genetic code evolution: The emergence of universality
Dynamics of genetic code evolution: The emergence of universality
复制标题
DOI:
10.1101/779959
复制
发表时间:
2019-09
期刊:
影响因子:
--
通讯作者:
J. Argyriadis;Yang-Hui He;Vishnu Jejjala;D. Minic
中科院分区:
文献类型:
--
作者:
J. Argyriadis;Yang-Hui He;Vishnu Jejjala;D. Minic
We study the dynamics of genetic code evolution. The algorithm of Vetsigian et al. [1] provides a solution that is both optimal and universal. We reproduce and analyze the algorithm as a dynamical system. All the parameters used in the model are varied to assess their impact on achieving universality. We show that by allowing specific parameters to vary with time, the algorithm converges much faster to a universal solution. Finally, we study automorphisms of the genetic code arising due to this model. We use this to examine the scaling of the solutions in order to understand the origin of universality and find that there is a direct link to mutation rate.