SUBSEGMENTAL TRANSCATHETER ARTERIAL EMBOLIZATION FOR SMALL HEPATOCELLULAR CARCINOMAS - LOCAL THERAPEUTIC EFFECT AND 5-YEAR SURVIVAL RATE

SUBSEGMENTAL TRANSCATHETER ARTERIAL EMBOLIZATION FOR SMALL HEPATOCELLULAR CARCINOMAS - LOCAL THERAPEUTIC EFFECT AND 5-YEAR SURVIVAL RATE
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DOI:
10.1007/bf00686674
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发表时间:
1994-02-01
影响因子:
3
通讯作者:
DEMACHI, H
DEMACHI, H
中科院分区:
医学3区
文献类型:
--
作者:
MATSUI, O;KADOYA, M;DEMACHI, H

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回顾性分析小肝癌经肝动脉亚段栓塞(TAE)治疗的局部疗效和5年生存率。100例肝硬化患者中共有124个直径小于4 cm的结节型HCC病灶进行了分析。所有病变在数字减影血管造影上变得不透明。11个切除病灶中64%完全坏死。在其余113处病变中,1次TAE后的1年和5年局部复发率分别为18%和33%。1年和5年生存率分别为100%和53%。TAE治疗后未见明显副作用。与常规TAE治疗相比,亚段TAE治疗显著提高了合并肝硬化的小肝癌患者的长期生存率。
The local therapeutic effects and 5-year survival rates obtained following subsegmental transcatheter arterial embolization (TAE) therapy for small hepatocellular carcinomas (HCCs) were retrospectively analyzed. A total of 124 nodular-type HCC lesions measuring less than 4 cm in diameter in 100 patients with liver cirrhosis were subjected to the analysis. All lesions became opaque on digital subtraction angiography. Complete necrosis was seen in 64% of 11 resected lesions. Among the remaining 113 lesions, the 1- and 5-year local recurrence rates following one performance of TAE were 18% and 33%, respectively. The 1- and 5-year survival rates were 100% and 53%, respectively. No significant side effect was observed after TAE therapy. Subsegmental TAE therapy significantly improved the long-term survival rates of patients with small HCCs associated with liver cirrhosis as compared with those treated by conventional TAE therapy.