Sex differences in behavioral strategies: avoiding interpretational pitfalls
Sex differences in behavioral strategies: avoiding interpretational pitfalls
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DOI：
10.1016/j.conb.2018.01.007
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发表时间：
2018-04-01
影响因子：
5.7
通讯作者：
Shansky, Rebecca M.
中科院分区：
文献类型：
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作者：
Shansky, Rebecca M.
尽管有足够的证据表明，大脑结构和功能存在性别差异，但我们对行为的神经生物学基础的理解几乎完全来自雄性动物。随着神经科学家开始遵守NIH最近的要求，即生物医学研究人员在研究中包括两性，我们在经典啮齿动物行为模型中解释结果的方式值得更仔细的审查和更细致的评估。在这篇小型综述中，我们重点介绍了最近在学习、决策和空间导航范式方面的性别差异论文，这些论文强调了认知能力与行为策略之间的区别，这些策略可能会给男性和女性带来独特的好处。
Despite ample evidence for sex differences in brain structure and function, our understanding of the neurobiological basis of behavior comes almost exclusively from male animals. As neuroscientists move to comply with recent NIH mandates that biomedical researchers include both sexes in their studies, the ways we interpret outcomes in classic rodent behavioral models deserve closer scrutiny and more nuanced evaluation. In this mini-review, we highlight recent sex differences papers in learning, decision-making, and spatial navigation paradigms that underscore the distinctions between cognitive capabilities versus behavioral strategies that may confer unique benefits to males and females.