Optically modulated fluorophores for selective fluorescence signal recovery.
Optically modulated fluorophores for selective fluorescence signal recovery.
复制标题
DOI:
10.1021/ja809785s
复制
发表时间:
2009-04-08
影响因子:
15
通讯作者:
Dickson RM
中科院分区:
文献类型:
--
作者:
Richards CI;Hsiang JC;Senapati D;Patel S;Yu J;Vosch T;Dickson RM
Fluorescence imaging in biological sciences is hindered by significant depth-dependent signal attenuation and high fluorescent backgrounds. We have developed optically modulated near-IR-emitting few-atom Ag nanodots that are selectively and dynamically photobrightened upon simultaneous excitation with a secondary laser enabling high sensitivity image extraction to reveal only the demodulated fluorophores. Image demodulation is demonstrated in high background environments to extract weak signals from completely obscuring background emission.
登录
查看更多内容
影响因子:
15
作者:
Steinhauer, Christian;Forthmann, Carsten;Tinnefeld, Philip
通讯作者:
Tinnefeld, Philip
影响因子:
48
作者:
Biteen, Julie S.;Thompson, Michael A.;Tselentis, Nicole K.;Bowman, Grant R.;Shapiro, Lucy;Moerner, W. E.
通讯作者:
Moerner, W. E.
影响因子:
56.9
作者:
Elf, Johan;Li, Gene-Wei;Xie, X. Sunney
通讯作者:
Xie, X. Sunney
影响因子:
56.9
作者:
Bates, Mark;Huang, Bo;Zhuang, Xiaowei
通讯作者:
Zhuang, Xiaowei
影响因子:
56.9
作者:
Kural, C;Kim, H;Selvin, PR
通讯作者:
Selvin, PR