Plasma Corin Levels Provide Minimal Prognostic Utility Incremental to Natriuretic Peptides in Chronic Systolic Heart Failure

Plasma Corin Levels Provide Minimal Prognostic Utility Incremental to Natriuretic Peptides in Chronic Systolic Heart Failure
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DOI:
10.1016/j.cardfail.2010.03.010
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发表时间:
2010-08-01
影响因子:
6
通讯作者:
Tang, W. H. Wilson
Tang, W. H. Wilson
中科院分区:
医学2区
文献类型:
--
作者:
Shrestha, Kevin;Troughton, Richard W.;Tang, W. H. Wilson

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背景资料:Corm是一种老年蛋白酶,可将前心房肽和前B型利钠肽裂解为具有生物活性的激素。血浆可溶性Corm水平、血浆利钠肽水平与心肌结构和性能的关系。方法和结果:在126例慢性收缩性心力衰竭(左心室射血分数)患者中,
Background: Corm is a senile protease that cleaves pro-atrial and pro-B-type natriuretic peptides into biologically active hormones The relationship between soluble plasma corm levels, plasma natriuretic peptide levels, myocardial structure and performance. and long-term clinical outcomes in the setting of chronic systolic heart failure has not been describedMethods and Results: In 126 patients with chronic systolic heart failure (left ventricular ejection fraction