Identification of pectenotoxins in plankton, filter feeders, and isolated cells of a Dinophysis acuminata with an atypical toxin profile, from Chile
Identification of pectenotoxins in plankton, filter feeders, and isolated cells of a Dinophysis acuminata with an atypical toxin profile, from Chile
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DOI：
10.1016/j.toxicon.2006.11.013
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发表时间：
2007-04-01
期刊：
影响因子：
2.8
通讯作者：
Uribe, Eduardo
中科院分区：
文献类型：
--
作者：
Blanco, Juan;Alvarez, Gonzalo;Uribe, Eduardo
2005 年秋季，Dinophys acuminata 的大量繁殖导致智利 III 区巴伊亚英格莱萨的扇贝捕捞活动停止。该恐龙物种的分离细胞显示含有 180pgcell(-1) 果胶毒素 2，但不含冈田酸或其任何类似物或衍生物（至少在可检测水平）。对覆盖面积约 100 平方公里的浮游生物和滤食性动物样本进行检查。从记录毒性的地点到巴伊亚东戈伊 (Bahia Tongoy) 350 公里，表明在第一次水花中发现的独特毒素分布在智利该地区广泛存在，并持续了数月。采用正电离模式的HPLC-ESI-MS进行分析，检测限低于2 ng OA mL(-1)甲醇提取物。这是关于美国太平洋沿岸浮游生物和所研究的滤食性动物中存在果胶毒素的第一份报告。这也是首次报道甲藻属物种含有果胶毒素，但不含任何冈田酸族毒素。 (c) 2006 Elsevier Ltd. 保留所有权利。
A bloom of Dinophysis acuminata produced, in autumn of 2005, a closure of the scallop harvesting in Bahia Inglesa, in the Chilean III region. Isolated cells of this Dinophysis species were shown to contain 180pgcell(-1) of pectenotoxin 2 but neither okadaic acid nor any of its analogs or derivatives (at least at a detectable level). Examination of plankton and filterfeeder samples covering an area of ca. 350 km, from the location where the toxicity was recorded to Bahia Tongoy, showed that the unique toxin profile found in the first bloom was widespread over that part of Chile and persisted for months. The analysis were carried out by HPLC-ESI-MS using positive ionization mode, with a detection limit below 2 ng of OA mL(-1) of methanolic extract. This is the first report of the presence of pectenotoxins in the plankton of the Pacific coast of America and in the studied filter feeders. This is also the first report of a Dinophysis species containing pectenotoxins and not any toxin of the okadaic acid group. (c) 2006 Elsevier Ltd. All rights reserved.