A score of non-contrast transthoracic echocardiography to screen patent foramen ovale in patients with embolic stroke of undetermined source.
A score of non-contrast transthoracic echocardiography to screen patent foramen ovale in patients with embolic stroke of undetermined source.
复制标题
非对比经胸超声心动图评分用于筛查不明原因栓塞性卒中患者卵圆孔未闭
DOI:
10.1186/s12883-022-02565-w
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发表时间:
2022-02-04
期刊:
影响因子:
2.6
通讯作者:
Cao W
中科院分区:
文献类型:
--
作者:
Zhang H;Tang H;Wu F;Yu C;Dong Q;Cao W
BackgroundThe aim of this study was to develop a screening score system of non-contrast transthoracic echocardiography (TTE) for patent foramen ovale (PFO) in patients with embolic stroke of undetermined source (ESUS).MethodsWe performed a retrospective analysis of 218 consecutive patients with a recent ESUS from 2015 to 2018, who received TTE and transcranial Doppler (TCD) as routine examinations. PFO was diagnosed by the bubble test of TCD. Significant differences of the non-contrast TTE findings and patient characteristics between PFO group and non-PFO group were selected into a score.ResultsPFO was diagnosed in 35.8% (78/218) of the patients. Compared with non-PFO group, a larger median aortic root diameter (ARd) (34 mm vs. 32 mm,p= 0.005), a lower median peak E wave velocity (Em) (61.5 cm/s vs. 68 cm/s,p= 0.005) and a lower incidence rate of mitral regurgitation (34.6% vs. 50.7%,p= 0.022) were seen in PFO group. ARd>33 mm and Em < 72 cm/s were the best thresholds to predict PFO in ROC analysis. A four-point score system (MEAD) including TTE criteria (including ARd>33 mm, Em < 72 cm/s and without mitral regurgitation) and no history of diabetes predicted PFO with an area under curve of 0.67 (95%CI 0.57–0.72,p< 0.001). MEAD score ≥ 3 was the best threshold to predict PFO with an accuracy of 0.64 (95% CI 0.57–0.7), a sensitivity of 0.65 (95% CI 0.53–0.75) and a specificity of 0.63 (95% CI 0.55–0.71).ConclusionThe MEAD score measured with non-contrast TTE can be used to select patients for bubble test of TCD to increase the diagnostic yield of PFO after ESUS.
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影响因子:
9.9
作者:
Kent, David M.;Ruthazer, Robin;Thaler, David E.
通讯作者:
Thaler, David E.
DOI:
10.1136/heartjnl-2016-310894
发表时间:
2017-11
期刊:
Heart (British Cardiac Society)
影响因子:
--
作者:
Andell P;Li X;Martinsson A;Andersson C;Stagmo M;Zöller B;Sundquist K;Smith JG
通讯作者:
Smith JG
影响因子:
19.7
作者:
Blersch, WK;Draganski, BM;Hölscher, T
通讯作者:
Hölscher, T
影响因子:
15.8
作者:
Rahimi K;Mohseni H;Otto CM;Conrad N;Tran J;Nazarzadeh M;Woodward M;Dwyer T;MacMahon S
通讯作者:
MacMahon S
影响因子:
1.9
作者:
Komar M;Olszowska M;Przewłocki T;Podolec J;Stępniewski J;Sobień B;Badacz R;Kabłak-Ziembicka A;Tomkiewicz-Pająk L;Podolec P
通讯作者:
Podolec P