Controllable doping of Fe atoms into MoS2 nanosheets towards peroxidase-like nanozyme with enhanced catalysis for colorimetric analysis of glucose
Controllable doping of Fe atoms into MoS2 nanosheets towards peroxidase-like nanozyme with enhanced catalysis for colorimetric analysis of glucose
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DOI：
10.1016/j.apsusc.2022.152496
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发表时间：
2022-01-20
影响因子：
6.7
通讯作者：
Wang, Hua
中科院分区：
文献类型：
--
作者：
Feng, Luping;Zhang, Lixiang;Wang, Hua
通过一锅水热法简单地将Fe元素掺杂到MoS 2纳米片中，从而产生具有显着增强的催化作用的过氧化物酶样纳米酶。结果表明，Fe-MoS 2催化剂的催化活性随Mo/Fe摩尔比的变化而变化，当Mo/Fe摩尔比为3/1时，催化活性最高，催化效率比原始MoS 2提高3倍以上。Fe-MoS 2纳米酶催化性能的显著提高是由于掺杂的Fe原子和Mo-S位的协同作用。一方面，在本文中，铁网站可能作为电子传递介质，以促进过氧化物酶样催化反应，证实了细胞色素C为基础的电子传递实验。另一方面，Mo-S位可能进行类Fenton反应的催化行为，如由羟基自由基捕获实验所揭示的。此外，开发的Fe-MoS 2纳米酶的比色方法的实际应用的可行性证明了血液样品中的葡萄糖。重要的是，由此可以深入了解通过掺杂Fe等杂原子设计的具有增强催化作用的不同纳米酶的设计，有望在生物医学分析，食品安全和环境监测领域中的基于催化的应用。
MoS2 nanosheets were doped with Fe elements simply via the one-pot hydrothermal route resulting in the peroxidase-like nanozymes with dramatically enhanced catalysis. It was discovered that the resulted Fe-MoS2 could display controllable catalysis activities depending on the Mo-to-Fe molar ratios, among which the highest one was achieved at 3/1 with catalysis efficiency over three folds higher than that of pristine MoS2. The greatly improved catalysis performances of Fe-MoS2 nanozyme are thought to be resulted from the synergistic effects of the doped Fe atom and Mo-S sites. On the one hand, herein, the Fe sites might serve as the electron transferring mediators to facilitate the peroxidase-like catalytic reactions, as confirmed by the cytochrome C-based electron transportation experiments. On the other hand, the Mo-S sites might conduct the catalytic behavior of Fenton-like reactions, as revealed by the hydroxyl radicals-capturing experiments. Furthermore, the feasibility of practical applications for the developed Fe-MoS2 nanozyme based colorimetric methods was demonstrated for glucose in blood sample. Importantly, an insight can be thereby obtained into the design of different nanozymes with enhanced catalysis designed by doping heteroatoms like Fe, promising for the catalysis-based applications in the biomedical analysis, food safety, and environmental monitoring fields.