Prevalence and distribution of ossification of the supra/interspinous ligaments in symptomatic patients with cervical ossification of the posterior longitudinal ligament of the spine: a CT-based multicenter cross-sectional study.
Prevalence and distribution of ossification of the supra/interspinous ligaments in symptomatic patients with cervical ossification of the posterior longitudinal ligament of the spine: a CT-based multicenter cross-sectional study.
复制标题
脊柱后纵韧带的宫颈骨化患者中骨上韧带的骨化的患病率和分布：一项基于CT的多中心横截面研究。
DOI：
10.1186/s12891-016-1350-y
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发表时间：
2016-12-01
影响因子：
2.3
通讯作者：
Kawaguchi Y
中科院分区：
文献类型：
--
作者：
Mori K;Yoshii T;Hirai T;Iwanami A;Takeuchi K;Yamada T;Seki S;Tsuji T;Fujiyoshi K;Furukawa M;Nishimura S;Wada K;Koda M;Furuya T;Matsuyama Y;Hasegawa T;Takeshita K;Kimura A;Abematsu M;Haro H;Ohba T;Watanabe M;Katoh H;Watanabe K;Ozawa H;Kanno H;Imagama S;Ito Z;Fujibayashi S;Yamazaki M;Matsumoto M;Nakamura M;Okawa A;Kawaguchi Y
棘上/棘间韧带连接相邻的棘突并充当脊柱的稳定器。与其他脊柱韧带一样，它可能会骨化。然而，很少有报道讨论骨化上/棘间韧带（OSIL），因此其流行病学仍然是未知的。因此，我们的目的是调查OSIL的患病率和分布在症状性颈椎后纵韧带骨化症（OPLL）患者。我们研究的参与者是有症状的颈椎OPLL患者，通过颈椎标准X线片诊断。全脊柱CT数据以及年龄和性别等临床参数来自日本脊柱韧带骨化多中心研究组织（JOSL）的20家机构。本文综述了OSIL的患病率、分布以及OSIL与临床指标的关系。还调查了OPLL（OP指数）和OSIL（OI指数）所涉及的水平之和以及项韧带骨化（ONL）的患病率。共招募了234例患者，平均年龄为65岁。在68名（54名男性和14名女性）患者（29%）中观察到基于CT的OSIL证据。OSIL的分布以胸部为主。在OSIL阳性患者中，19例（28%）单节段受累，49例（72%）多节段受累。我们发现OP指数等级和OSI指数之间存在显著的正相关。与阴性患者相比，OSIL阳性患者的ONL发生率显著较高。有症状的颈椎OPLL患者中OSIL的患病率为29%。OSIL的分布以胸部为主。
Supra/interspinous ligaments connect adjacent spinous processes and act as a stabilizer of the spine. As with other spinal ligaments, it can become ossified. However, few report have discussed ossification supra/interspinous ligaments (OSIL), so its epidemiology remains unknown. We therefore aimed to investigate the prevalence and distribution of OSIL in symptomatic patients with cervical ossification of the posterior longitudinal ligament (OPLL). The participants of our study were symptomatic patients with cervical OPLL who were diagnosed by standard radiographs of the cervical spine. The whole spine CT data as well as clinical parameters such as age and sex were obtained from 20 institutions belong to the Japanese Multicenter Research Organization for Ossification of the Spinal Ligament (JOSL). The prevalence and distribution of OSIL and the association between OSIL and clinical parameters were reviewed. The sum of the levels involved by OPLL (OP-index) and OSIL (OSI-index) as well as the prevalence of ossification of the nuchal ligament (ONL) were also investigated. A total of 234 patients with a mean age of 65 years was recruited. The CT-based evidence of OSIL was noted in 68 (54 males and 14 females) patients (29%). The distribution of OSIL showed a significant thoracic preponderance. In OSIL-positive patients, single-level involvement was noted in 19 cases (28%), whereas 49 cases (72%) presented multi-level involvement. We found a significant positive correlation between the OP-index grade and OSI-index. ONL was noted at a significantly higher rate in OSIL-positive patients compared to negative patients. The prevalence of OSIL in symptomatic patients with cervical OPLL was 29%. The distribution of OSIL showed a significant thoracic preponderance.