Taxonomic distribution and quantitative analysis of free purine and pyrimidine nucleosides in snake venoms

Taxonomic distribution and quantitative analysis of free purine and pyrimidine nucleosides in snake venoms
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DOI:
10.1016/j.cbpc.2004.09.020
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发表时间:
2005-01-01
影响因子:
2.2
通讯作者:
Aird, SD
Aird, SD
中科院分区:
生物学3区
文献类型:
--
作者:
Aird, SD

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本文对32种眼镜蛇和蝰蛇毒的核苷含量进行了测定。游离嘌呤,主要是腺苷(ADO),肌苷(INO)和鸟苷(GUA),包括高达8.7%的固体成分的一些毒液。因此,在某些毒液中,纯度比许多蛋白质毒素要丰富得多。次黄嘌呤(HYP)存在于大约一半的眼镜蛇和蝰蛇毒液中,是其中相对次要的成分(
The nucleoside content of 32 elapid and viperid venoms was examined. Free purines, principally adenosine (ADO), inosine (INO), and guanosine (GUA), comprised as much as 8.7% of the solid components of some venoms. Thus, purities are far more abundant in some venoms than many proteinaceous toxins. Hypoxanthine (HYP) was found in about half of elapid and viperine venoms, in which it is a relatively minor constituent (