Antidiabetic activity of the rhizoma of Anemarrhena asphodeloides and active components, mangiferin and its glucoside

Antidiabetic activity of the rhizoma of Anemarrhena asphodeloides and active components, mangiferin and its glucoside
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DOI:
10.1248/bpb.24.1009
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发表时间:
2001-09-01
影响因子:
2
通讯作者:
Tanigawa, K
Tanigawa, K
中科院分区:
医学4区
文献类型:
--
作者:
Miura, T;Ichiki, H;Tanigawa, K

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采用遗传性2型糖尿病动物模型KK-Ay小鼠,研究了知母根茎的抗糖尿病活性。黄芪水提物(AA)(90 mg/kg)经口给药后7 h,血糖水平从570 +/- 29降至401 +/- 59 mg/dl(p
The antidiabetic activity of the rhizoma of Anemarrhena asphodeloides was investigated in KK-Ay mice, an animal model of genetic type 2 diabetes. The water extract of the rhizoma (AA) (90 mg/kg) reduced blood glucose levels from 570 +/- 29 to 401 +/- 59 mg/dl 7 h after oral administration (p