ETS transcription factors in embryonic vascular development.
ETS transcription factors in embryonic vascular development.
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胚胎血管发育中的 ETS 转录因子。
DOI：
10.1007/s10456-016-9511-z
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发表时间：
2016-07
期刊：
影响因子：
9.8
通讯作者：
Sumanas S
中科院分区：
文献类型：
--
作者：
Craig MP;Sumanas S
至少有13个Ets结构域转录因子在胚胎造血或血管发育过程中表达，并可能在胚胎血管或血统的形成和维持中发挥作用。本文综述了目前我们对ETS因子在血管生成和血管生成中所起的具体作用以及它们之间功能冗余的意义的认识。
At least thirteen ETS-domain transcription factors are expressed during embryonic hematopoietic or vascular development and potentially function in the formation and maintenance of the embryonic vasculature or blood lineages. This review summarizes our current understanding of the specific roles played by ETS factors in vasculogenesis and angiogenesis and the implications of functional redundancies between them.