Auditory arousal thresholds during sleep in hyperkinetic children.
Auditory arousal thresholds during sleep in hyperkinetic children.
复制标题
多动儿童睡眠期间的听觉唤醒阈值。
作者：
K. Busby;R. T. Pivik
在青春期前未服药和服药的多动和正常对照男性儿童的整个睡眠（4晚协议）的听觉唤醒阈值进行了测定。最引人注目的结果是，即使在高达123分贝声压级的强度下，所有组的儿童也普遍无法引起行为反应。在所有的唤醒尝试中，52.5%导致非唤醒，13%导致部分非持续的生理唤醒反应，34.3%与完全唤醒相关。一个显着增加的比例觉醒和减少的频率nonarousals发生在整个晚上。两组在唤醒反应的数量上没有差异。虽然未服药的多动症儿童往往有较低的觉醒阈值相对于儿童在两个比较组，唯一显着的组间差异是一个较低的阈值反应在未服药的，相对于服药，多动症受试者在第2阶段睡眠。接受兴奋剂药物治疗的多动儿童的唤醒阈值接近正常对照儿童。非药物治疗的多动受试者在睡眠期间对听觉刺激的敏感性增强被解释为表明负责提高唤醒阈值的过程在这个时候在这些儿童中不太有效。
Auditory arousal thresholds were determined throughout sleep (4-night protocol) in prepubertal nonmedicated and medicated hyperkinetic and normal control male children. The most striking result was the general inability to arouse children of all groups to behavioral response even at intensities up to 123 dB sound pressure level. Of total awakening attempts, 52.5% resulted in non-arousal, 13% resulted in partial, nonsustained physiological arousal responses, and 34.3% were associated with complete awakenings. A significant increase in proportion of awakenings and decrease in the frequency of nonarousals occurred across the night. The groups did not differ with respect to the number of arousal responses. Although nonmedicated hyperkinetic children tended to have lower arousal thresholds relative to children in both comparison groups, the only significant group difference was a lower threshold response in nonmedicated, relative to medicated, hyperkinetic subjects during stage 2 sleep. Arousal thresholds in hyperkinetic children receiving stimulant medication approximated those of normal control children. The enhanced sensitivity of nonmedicated hyperkinetic subjects to auditory stimuli during sleep is interpreted as indicating that processes responsible for elevating arousal threshold at this time are less effective in these children.