Multinucleation of spermatozoa and spermatids in infertile men chronically exposed to carbofuran
Multinucleation of spermatozoa and spermatids in infertile men chronically exposed to carbofuran
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DOI：
10.1016/j.reprotox.2010.03.007
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发表时间：
2010-07-01
影响因子：
3.3
通讯作者：
Jaramillo-Rangel, Gilberto
中科院分区：
文献类型：
--
作者：
Gallegos-Avila, Guadalupe;Ancer-Rodriguez, Jesus;Jaramillo-Rangel, Gilberto
目的：目的：报道2例因长期接触克百威而不育的男性精液标本的检测结果。通过光学显微镜进行了形态学分析。结果：精液分析显示，在第一种情况下，总浓度为42万精子/mL，17%的活力和20%的正常形状。第二例患者的总浓度为500万个精子/mL，活动率为6%，正常形状为2%。患者提出了类似的比例的双核精子（28和26%）和多核精子细胞（10和6%）。结论：据我们所知，这是第一次，男性暴露于呋喃丹精液样本的变化报告。需要在这一领域进行更多的研究，以便就这一问题得出结论。(C)2010年爱思唯尔公司All rights reserved.
Objective: To report the findings encountered in semen samples coming from two infertile men chronically exposed to carbofuran.Methods: Semen samples were collected and analyzed as recommended by the World Health Organization. A morphological analysis was carried out by light microscopy.Results: Seminal analysis revealed in the first case a total concentration of 42 million spermatozoa/mL with 17% motility and 20% normal shape. The second patient presented a total concentration of 5 million spermatozoa/mL with 6% motility and 2% normal shape. The patients presented a similar percentage of binucleated spermatozoa (28 and 26%) and of multinucleated spermatids (10 and 6%).Conclusion: To our knowledge, this is the first time that alterations in semen samples of men exposed to carbofuran are reported. More research in this area is needed to make conclusions on the subject. (C) 2010 Elsevier Inc. All rights reserved.