Characteristics of users of online personalized genomic risk assessments: Implications for physician-patient interactions
Characteristics of users of online personalized genomic risk assessments: Implications for physician-patient interactions
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DOI：
10.1097/gim.0b013e3181b22c3a
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发表时间：
2009-08-01
影响因子：
8.8
通讯作者：
Brody, Lawrence C.
中科院分区：
文献类型：
--
作者：
McBride, Colleen M.;Alford, Sharon Hensley;Brody, Lawrence C.
目的：评估哪些心理和行为因素预测谁可能寻求基于SNP的基因检测来治疗多种常见的健康状况，其中反馈可用于激励一级预防。方法：对一家大型管理式医疗机构登记的25-40岁成年人进行调查。那些符合条件的人可以登录一个安全的研究网站，查看有关基于SNP的基因检测的风险和益处的信息，并要求免费检测。两个主要结果是解决：访问网络（是或否）和决定进行测试（完成在诊所抽血）结果：那些考虑遗传易感性测试没有持有遗传决定论的信念（0 [行为]到1 [遗传]的量表上的0.42），但相信遗传信息是有价值的，并相信他们可以理解这些信息。那些认为了解遗传学很重要的人（优势比= 1.28），相信他们可以理解遗传学（优势比= 1.26），并报告最需要改变的健康习惯（优势比= 1.39）最有可能接受测试。结论：向医疗保健提供者提供在线遗传学信息的个人可能是最有动力采取措施实现更健康生活方式的人。这些动机可能被卫生保健提供者用来促进积极的健康结果。Genet Med 2009：11（8）：582-587.
Purpose: To evaluate what psychological and behavioral factors predict who is likely to seek SNP-based genetic tests for multiple common health conditions where feedback can be used to motivate primary prevention. Methods: Adults aged 25-40 years who were enrolled in a large managed care organization were surveyed. Those eligible could log on to a secure study Web site to review information about the risks and benefits of a SNP-based genetic test and request free testing. Two primary outcomes are addressed: accessing the Web (yes or no) and deciding to be tested (completed a blood draw at the clinic) Results: Those considering genetic susceptibility testing did not hold genetically deterministic beliefs (0.42 on scale of 0 [behavior] to 1 [genetic]) but believed genetic information to be valuable and were confident they could understand such information. Individuals who believed it important to learn about genetics (odds ratio = 1.28), were confident they could understand genetics (odds ratio = 1.26), and reported the most health habits to change (odds ratio = 1.39) were most likely to get tested. Conclusions: Individuals who present to health care providers with online genetics information may be among the most motivated to take steps toward healthier lifestyles. These motives might be leveraged by health care providers to promote positive health outcomes. Genet Med 2009:11(8):582-587.