Redox homeostasis and antioxidant signaling: A metabolic interface between stress perception and physiological responses
Redox homeostasis and antioxidant signaling: A metabolic interface between stress perception and physiological responses
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DOI：
10.1105/tpc.105.033589
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发表时间：
2005-07-01
期刊：
影响因子：
11.6
通讯作者：
Noctor, G
中科院分区：
文献类型：
--
作者：
Foyer, CH;Noctor, G
低分子量抗氧化剂，如抗坏血酸、谷胱甘肽和生育酚，是信息丰富的氧化还原缓冲液，可与许多细胞成分相互作用。除了在防御和作为酶辅助因子的关键作用外，细胞抗氧化剂还通过调节从有丝分裂和细胞伸长到衰老和死亡的过程来影响植物的生长和发育（De Pinto和De Gara, 2004； Potters等人，2004；Tokunaga等人，2005）。最重要的是，抗氧化剂提供细胞氧化还原状态的基本信息，它们影响与生物和非生物应激反应相关的基因表达，以最大限度地防御。越来越多的证据表明一个氧化还原稳态模型，其中活性氧(ROS) -抗氧化剂相互作用作为代谢和环境信号的代谢接口。这个接口调节适当的诱导适应过程，或者，细胞死亡程序的执行。
Low molecular weight antioxidants, such as ascorbate, glutathione, and tocopherol, are information-rich redox buffers that interact with numerous cellular components. In addition to crucial roles in defense and as enzyme cofactors, cellular antioxidants influence plant growth and development by modulating processes from mitosis and cell elongation to senescence and death (De Pinto and De Gara, 2004; Potters et al., 2004; Tokunaga et al., 2005). Most importantly, antioxidants provide essential information on cellular redox state, and they influence gene expression associated with biotic and abiotic stress responses to maximize defense. Growing evidence suggests a model for redox homeostasis in which the reactive oxygen species (ROS)–antioxidant interaction acts as a metabolic interface for signals derived from metabolism and from the environment. This interface modulates the appropriate induction of acclimation processes or, alternatively, execution of cell death programs.