Brief report: Primary human herpesvirus 6 infection in a patient following liver transplantation from a seropositive donor
Brief report: Primary human herpesvirus 6 infection in a patient following liver transplantation from a seropositive donor
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简要报告：血清阳性供体肝移植后患者发生原发性人类疱疹病毒 6 感染
DOI：
10.1002/jmv.1890280203
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发表时间：
1989
影响因子：
12.7
通讯作者：
S. Efstathiou
中科院分区：
文献类型：
--
作者：
K. Ward;J. Gray;S. Efstathiou
从一例肝移植术后23天患者的外周血淋巴细胞中分离到一株病毒，经阴性对照、切片、DNA杂交和免疫荧光鉴定为人类疱疹病毒6型(HHV-6)。这名患者在接受血清阳性捐赠者的肝脏之前，HHV-6抗体呈血清阴性。Ig M和Ig G抗体的血清转换与病毒血症同时发生，表明对HHV-6感染的主要反应可能是从供体肝脏获得的。感染与患者随后的疾病发作的关系进行了讨论。
A virus, isolated from peripheral blood lymphocytes of a patient 23 days after liver transplantation, was identified by negative contrast and thin‐section electron microscopy, DNA hybridisation, and immunofluorescence as human herpesvirus 6 (HHV‐6). The patient was seronegative for antibodies to HHV‐6 before receiving the liver from a seropositive donor. Seroconversion for IgM and IgG antibodies occurred at the same time as the viraemia, indicating a primary response to HHV‐6 infection that was probably acquired from the donor liver. The relationship of the infection to the patient's subsequent disease episodes is discussed.
121 例肝移植受者巨细胞病毒和其他疱疹病毒感染：通过捐赠器官传播以及 OKT3 抗体的作用。
DOI：
10.1093/infdis/158.1.124
发表时间：
1988
期刊：
The Journal of infectious diseases
影响因子：
--
作者：
Singh,N;Dummer,JS;Kusne,S;Breinig,MK;Armstrong,JA;Makowka,L;Starzl,TE;Ho,M
通讯作者：
Ho,M