Correlation between impedance cardiography and 6 min walk distance in atrial fibrillation patients.
Correlation between impedance cardiography and 6 min walk distance in atrial fibrillation patients.
复制标题
心房颤动患者阻抗心动图与6分钟步行距离的相关性
DOI：
10.1186/s12872-016-0297-0
复制
发表时间：
2016-06-10
影响因子：
2.1
通讯作者：
Zhou HL
中科院分区：
文献类型：
--
作者：
Ding L;Quan XQ;Zhang S;Ruan L;Zhang L;Zheng K;Yu WW;Wu XF;Mi T;Zhang CT;Zhou HL
房颤患者心阻抗图(ICG)与6m in步行距离(6MWD)的相关性尚不清楚。方法选择房颤患者49例(房颤患者21例，非房颤患者28例)，评价其血流动力学参数：心输出量(CO)、每搏量(SV)、每搏量指数(SVI)、左每搏做功(LSW)、左每搏做功指数(LSWI)、每搏血管阻力(SSVR)、每搏血管阻力指数(SSVRI)；结果房颤组CO明显低于对照组(2.26 ± 0.14vs 4.11 ± 0.20d，P= 0.039)，SVR显著高于对照组(677.60 ± 69.10vs 344.41 ± 22.98dynes/cm~5，p= 0.001)，SSVRI(396.97 ± 36.80vs 199.01 ± 11.72dynes/cm~5/m~2，p<)； 0.001)，而不是对照组。房颤组血浆NT-ProBNP(1409.48 ± 239.90 vs 332.59 ± 68.85 pg/ml，p= 0.001)显著高于对照组，6MWD(264.33 ± 14.55 vs 428.79 ± 29.98 mm，p<； 0.001)显著低于对照组。两组左心室射血分数差异无统计学意义(62.67 ± 7.62%vs 63.93 ± 5.03%，p= 0.470)。相关分析显示，房颤患者的CO(R = 0.494，p= 0.023)、SV(R = 0.633，p= 0.002)、Lsw(R = 0.615，p= 0.003)和LSWI(R = 0.491，p= 0.024)与6MWD呈显著正相关。心阻抗图测得的心输出量与房颤患者的6MWD呈显著正相关。
BackgroundThe correlation between impedance cardiography (ICG) and 6 min walk distance (6MWD) in atrial fibrillation (AF) patients remains unknown.MethodsWe recruited 49 subjects in the study (21 AF patients and 28 patients without AF) and estimated hemodynamic parameters: cardiac output (CO), stroke volume (SV), stroke volume index (SVI), left stroke work (LSW), left stroke work index (LSWI), stroke systemic vascular resistance (SSVR), stroke systemic vascular resistance index (SSVRI); 6MWD, left ventricle ejection fraction (LVEF), NT-pro brain natriuretic peptide (NT-pro BNP) for the two groups.ResultsThe AF group have apparently lower CO (2.26 ± 0.14 VS 4.11 ± 0.20 L/min,p= 0.039) and distinctly higher SVR (677.60 ± 69.10 VS 344.41 ± 22.98 dynes/cm5,p= 0.001), SSVRI (396.97 ± 36.80 VS 199.01 ± 11.72 dynes/cm5/m2,p< 0.001) than the control group. NT-pro BNP (1409.48 ± 239.90 VS 332.59 ± 68.85 pg/ml,p= 0.001) in the AF group was significantly higher than the control group and 6MWD (264.33 ± 14.55 VS 428.79 ± 29.98 m,p< 0.001) in the AF group was lower than the control group. There was no significant difference in LVEF between the two groups (62.67 ± 7.62 % VS 63.93 ± 5.03 %,p= 0.470). Pearson correlation analysis revealed that CO (R = 0.494,p= 0.023), SV (R = 0.633,p= 0.002), LSW (R = 0.615,p= 0.003) and LSWI (R = 0.491,p= 0.024) significantly correlated positively with 6MWD in AF patients.ConclusionsAF patients had lower cardiac output, shorter 6MWD and higher NT-pro BNP than patients with sinus rhythm. The cardiac output measured by impedance cardiography significantly correlated positively with 6MWD in AF patients.