The Anopheles gambiae genome:: an update

The Anopheles gambiae genome:: an update
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DOI:
10.1016/j.pt.2003.11.003
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发表时间:
2004-02-01
影响因子:
9.6
通讯作者:
Collins, FH
Collins, FH
中科院分区:
医学1区
文献类型:
--
作者:
Mongin, E;Louis, C;Collins, FH

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经过国际合作,冈比亚按蚊基因组序列的第一份草稿及其初步注释于2002年10月发表。此后,《安》的编纂、注释和入编方式都发生了很大变化。冈比亚基因组不断发展。本文回顾了当前序列组装和基因注释的进展,并考虑了其局限性,以及解决这些问题的方法和数据用户必须牢记的突出问题。
As a result of an international collaborative effort, the first draft of the Anopheles gambiae genome sequence and its preliminary annotation were published in October 2002. Since then, the assembly, annotation and means of accession of the An. gambiae genome have been under continuous development. This article reviews progress and considers limitations in the current sequence assembly and gene annotation, as well as approaches to address these problems and outstanding issues that users of the data must bear in mind.