The First Total Synthesis of the (±)‐Palstatin
The First Total Synthesis of the (±)‐Palstatin
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DOI：
10.1002/cjoc.200690041
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发表时间：
2006-02
影响因子：
5.4
通讯作者：
Jian-Peng Feng;Xiao‐Long Wang;Xiao-Ping Cao
中科院分区：
文献类型：
--
作者：
Jian-Peng Feng;Xiao‐Long Wang;Xiao-Ping Cao
以市售的5-溴香豆素和2，4，6-三羟基苯乙酮为原料，首次实现了(±)-Palstatin的全合成。SeO2促进氧化环化反应，Ag2O催化氧化偶联反应是合成成功的关键步骤。
The first total synthesis of (±)-palstatin was achieved from commercially available 5-bromovanallin and 2,4,6-trihydroxyacetophenone. SeO2 promoted oxidative cyclization reaction and Ag2O catalyzed oxidative coupling reaction served as the key steps in the synthesis successfully.