PERIPHERAL AUTONOMIC SURFACE-POTENTIAL - A QUANTITATIVE TECHNIQUE FOR RECORDING SYMPATHETIC CONDUCTION IN MAN
PERIPHERAL AUTONOMIC SURFACE-POTENTIAL - A QUANTITATIVE TECHNIQUE FOR RECORDING SYMPATHETIC CONDUCTION IN MAN
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DOI：
10.1016/0022-510x(85)90120-0
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发表时间：
1985-01-01
影响因子：
4.4
通讯作者：
BAJADA, S
中科院分区：
文献类型：
--
作者：
KNEZEVIC, W;BAJADA, S
使用EMG [肌电图]设备与时间锁定记录和标准的平均设施，以前定义不明确的皮肤电位被记录。在30例正常人的手掌面和足底面记录到这种电位，我们称之为外周自主神经表面电位（PASP）。PASP通常由最初为负峰和随后为正峰的双相电位组成。它是由手腕正中神经上随机定时的电刺激引起的。平均手掌PASP潜伏期为1.52 ± 0.01。0.13平均足底PASP潜伏期为2.07 ± 0.001。0.16 S.手掌和足底PASP的平均振幅为479 ± 100。105 μ V和101 ±。40 μ V。计算出平均交感神经传导速度为1.28 ± 1.28。0.18 m/s.在5名正常人中，使用类似的技术记录左中指掌侧表面的PASP。阿托品离子导入记录部位下的皮肤可消除所有受试者的PASP。对10例糖尿病患者进行了掌跖PASP记录。波幅（掌侧179 . ±. 158 μ V，足底17 ±。16 μ V）与正常相比显著降低（P < 0.001）。对5例单侧腰或颈交感神经节切除术的患者进行了研究。所有患者交感神经切除术侧的PASP均缺失或明显降低。PASP可以证明是一个有用的交感神经功能的定量测试。
Using EMG [electromyograph] equipment with time locked recording and standard averaging facilities, a previously poorly defined skin potential was recorded. The potential, termed by us the peripheral autonomic surface potential (PASP), was recorded from the palmar surface of the hand and the plantar surface of the foot in 30 normal subjects. The PASP usually consisted of a biphasic potential with an initial negative and a later positive peak. It was elicited by randomly timed electrical stimuli over the median nerve at the wrist. The mean palmar PASP latency was 1.52 .+-. 0.13 s and the mean plantar PASP latency was 2.07 .+-. 0.16 s. The mean palmar and plantar PASP amplitudes were 479 .+-. 105 .mu.V and 101 .+-. 40 .mu.V, respectively. A mean sympathetic conduction velocity was calculated to be 1.28 .+-. 0.18 m/s. In 5 normal subjects a similar technique was used to record a PASP from the volar surface of the left middle finger. Iontophoresis of atropine into the skin under the recording site abolished the PASP in all subjects. Palmar and plantar PASPs were recorded in 10 diabetic patients. The amplitudes (palmar 179 .+-. 158 .mu.V, plantar 17 .+-. 16 .mu.V) were significantly reduced compared to normals (P < 0.001). Five patients with unilateral lumbar or cervical sympathectomy were studied. The PASP was absent or markedly reduced on the side of the sympathectomy in all patients. The PASP may prove a useful quantitative test of sympathetic function.