Predicting success: Patterns of cortical activation and deactivation prior to response inhibition
Predicting success: Patterns of cortical activation and deactivation prior to response inhibition
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DOI：
10.1162/089892904970726
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发表时间：
2004-06-01
影响因子：
3.2
通讯作者：
Garavan, H
中科院分区：
文献类型：
--
作者：
Hester, RL;Murphy, K;Garavan, H
本研究探讨了注意与反应抑制任务前的其他准备过程之间的关系以及反应抑制本身所涉及的过程。为了实现这一点，采用混合fMRI设计来识别在抑制决策事件和在2至7秒之前（提示期）引入视觉提示后的试验块期间激活的功能区。为成功的表现做准备，会增加额顶叶皮层网络中提示期和抑制本身的激活。此外，准备产生的激活减少中线区（ESTA和内侧前额叶）认为是负责监测内部情绪状态，这些线索期失活单独预测随后的成功或失败。结果表明，当提供的线索，以表示迫切需要的行为控制，成功的性能结果从一个协调的模式准备激活任务相关的领域和任务无关的失活。
The present study investigated the relationships between attention and other preparatory processes prior to a response inhibition task and the processes involved in the inhibition itself. To achieve this, a mixed fMRI design was employed to identify the functional areas activated during both inhibition decision events and the block of trials following a visual cue introduced 2 to 7 sec prior (cue period). Preparing for successful performance produced increases in activation for both the cue period and the inhibition itself in the frontoparietal cortical network. Furthermore, preparation produced activation decreases in midline areas (insula and medial prefrontal) argued to be responsible for monitoring internal emotional states, and these cue period deactivations alone predicted subsequent success or failure. The results suggest that when cues are provided to signify the imminent requirement for behavioral control, successful performance results from a coordinated pattern of preparatory activation in task-relevant areas and deactivation of task-irrelevant ones.